GNAI2

Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
Identifiers
Symbols	GNAI2 ; GIP; GNAI2B; H_LUCA15.1; H_LUCA16.1
External IDs	Template:OMIM5 Template:MGI HomoloGene: 55539
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, also known as GNAI2, is a human gene.

Further reading

• Sidhu A, Niznik HB (2000). "Coupling of dopamine receptor subtypes to multiple and diverse G proteins". Int. J. Dev. Neurosci. 18 (7): 669–77. PMID 10978845.
• Offermanns S, Schultz G, Rosenthal W (1991). "Evidence for opioid receptor-mediated activation of the G-proteins, Go and Gi2, in membranes of neuroblastoma x glioma (NG108-15) hybrid cells". J. Biol. Chem. 266 (6): 3365–8. PMID 1671672.CS1 maint: Multiple names: authors list (link)
• Cormont M, Le Marchand-Brustel Y, Van Obberghen E; et al. (1991). "Identification of G protein alpha-subunits in RINm5F cells and their selective interaction with galanin receptor". Diabetes. 40 (9): 1170–6. PMID 1718802.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Magovcevic I, Ang SL, Seidman JG; et al. (1992). "Regional localization of the human G protein alpha i2 (GNAI2) gene: assignment to 3p21 and a related sequence (GNAI2L) to 12p12-p13". Genomics. 12 (1): 125–9. PMID 1733849.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bushfield M, Murphy GJ, Lavan BE; et al. (1990). "Hormonal regulation of Gi2 alpha-subunit phosphorylation in intact hepatocytes". Biochem. J. 268 (2): 449–57. PMID 2114093.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lyons J, Landis CA, Harsh G; et al. (1990). "Two G protein oncogenes in human endocrine tumors". Science. 249 (4969): 655–9. PMID 2116665.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Osawa S, Dhanasekaran N, Woon CW, Johnson GL (1990). "G alpha i-G alpha s chimeras define the function of alpha chain domains in control of G protein activation and beta gamma subunit complex interactions". Cell. 63 (4): 697–706. PMID 2121366.CS1 maint: Multiple names: authors list (link)
• McClue SJ, Milligan G (1990). "The alpha 2B adrenergic receptor of undifferentiated neuroblastoma x glioma hybrid NG108-15 cells, interacts directly with the guanine nucleotide binding protein, Gi2". FEBS Lett. 269 (2): 430–4. PMID 2169434.
• Rudolph U, Koesling D, Hinsch KD; et al. (1989). "G-protein alpha-subunits in cytosolic and membranous fractions of human neutrophils". Mol. Cell. Endocrinol. 63 (1–2): 143–53. PMID 2502457.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lang JC, Costa T (1990). "Distribution of the alpha-subunit of the guanine nucleotide-binding protein Gi2 and its comparison to G alpha o.". J. Recept. Res. 9 (4–5): 313–29. PMID 2512386.
• Itoh H, Toyama R, Kozasa T; et al. (1988). "Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs". J. Biol. Chem. 263 (14): 6656–64. PMID 2834384.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Weinstein LS, Spiegel AM, Carter AD (1988). "Cloning and characterization of the human gene for the alpha-subunit of Gi2, a GTP-binding signal transduction protein". FEBS Lett. 232 (2): 333–40. PMID 2837412.CS1 maint: Multiple names: authors list (link)
• Didsbury JR, Ho YS, Snyderman R (1987). "Human Gi protein alpha-subunit: deduction of amino acid structure from a cloned cDNA". FEBS Lett. 211 (2): 160–4. PMID 3100330.CS1 maint: Multiple names: authors list (link)
• Beals CR, Wilson CB, Perlmutter RM (1987). "A small multigene family encodes Gi signal-transduction proteins". Proc. Natl. Acad. Sci. U.S.A. 84 (22): 7886–90. PMID 3120178.CS1 maint: Multiple names: authors list (link)
• Williamson EA, Ince PG, Harrison D; et al. (1995). "G-protein mutations in human pituitary adrenocorticotrophic hormone-secreting adenomas". Eur. J. Clin. Invest. 25 (2): 128–31. PMID 7737262.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Takigawa M, Sakurai T, Kasuya Y; et al. (1995). "Molecular identification of guanine-nucleotide-binding regulatory proteins which couple to endothelin receptors". Eur. J. Biochem. 228 (1): 102–8. PMID 7882989.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Grassie MA, Milligan G (1995). "Analysis of the relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these polypeptides in rat 1 fibroblasts". Biochem. J. 306 ( Pt 2): 525–30. PMID 7887906.
• Migeon JC, Thomas SL, Nathanson NM (1994). "Regulation of cAMP-mediated gene transcription by wild type and mutated G-protein alpha subunits. Inhibition of adenylyl cyclase activity by muscarinic receptor-activated and constitutively activated G(o) alpha". J. Biol. Chem. 269 (46): 29146–52. PMID 7961880.CS1 maint: Multiple names: authors list (link)
• Wennogle LP, Conder L, Winter C; et al. (1994). "Stabilization of C5a receptor--G-protein interactions through ligand binding". J. Cell. Biochem. 55 (3): 380–8. doi:10.1002/jcb.240550316. PMID 7962171.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Valet P, Senard JM, Devedjian JC; et al. (1993). "Characterization and distribution of alpha 2-adrenergic receptors in the human intestinal mucosa". J. Clin. Invest. 91 (5): 2049–57. PMID 8098045.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)