Firocoxib: Difference between revisions
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{{Drugbox | {{Drugbox | ||
| IUPAC_name | | verifiedrevid = 443742691 | ||
| image | | IUPAC_name = 3-(Cyclopropylmethoxy)-5,5-dimethyl-4-(4-methylsulfonylphenyl)furan-2-one | ||
| | | image = Firocoxib.png | ||
| | | image2 = Firocoxibgif.png | ||
| alt2 = Firocoxib molecule | |||
| | <!--Clinical data--> | ||
| tradename = Equioxx; Previcox | |||
| Drugs.com = {{drugs.com|international|firocoxib}} | |||
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> | |||
| | | pregnancy_US = <!-- A / B / C / D / X --> | ||
| pregnancy_category = | |||
| legal_AU = S4 | |||
| legal_CA = <!-- Schedule I, II, III, IV, V, VI, VII, VIII --> | |||
| legal_UK = POM | |||
| | | legal_US = Rx-only | ||
| | | legal_status = ''Veterinary use only'' | ||
| pregnancy_AU | |||
| pregnancy_US | |||
| pregnancy_category= | |||
| legal_AU = | |||
| legal_CA = | |||
| legal_UK = | |||
| legal_US = | |||
| legal_status | |||
| routes_of_administration = Oral | | routes_of_administration = Oral | ||
<!--Pharmacokinetic data--> | |||
| bioavailability = | |||
| protein_bound = | |||
| metabolism = | |||
| elimination_half-life = | |||
| excretion = | |||
<!--Identifiers--> | |||
| CAS_number = 189954-96-9 | |||
| ATCvet = yes | |||
| ATC_prefix = M01 | |||
| ATC_suffix = AH90 | |||
| ATC_supplemental = | |||
| PubChem = 208910 | |||
| DrugBank_Ref = {{drugbankcite|correct|drugbank}} | |||
| DrugBank = | |||
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | |||
| ChemSpiderID = 181008 | |||
| UNII_Ref = {{fdacite|correct|FDA}} | |||
| UNII = Y6V2W4S4WT | |||
| KEGG_Ref = {{keggcite|correct|kegg}} | |||
| KEGG = D03712 | |||
| ChEBI = 76136 | |||
| ChEMBL_Ref = {{ebicite|correct|EBI}} | |||
| ChEMBL = 69998 | |||
<!--Chemical data--> | |||
| chemical_formula = | |||
| C=17 | H=20 | O=5 | S=1 | |||
| molecular_weight = 336.402 g/mol | |||
| smiles = O=C2OC(C(=C2\OCC1CC1)\c3ccc(cc3)S(=O)(=O)C)(C)C | |||
| InChI = 1/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3 | |||
| InChIKey = FULAPETWGIGNMT-UHFFFAOYAT | |||
| StdInChI_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChI = 1S/C17H20O5S/c1-17(2)14(12-6-8-13(9-7-12)23(3,19)20)15(16(18)22-17)21-10-11-4-5-11/h6-9,11H,4-5,10H2,1-3H3 | |||
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | |||
| StdInChIKey = FULAPETWGIGNMT-UHFFFAOYSA-N | |||
}} | }} | ||
__NOTOC__ | |||
'''Firocoxib''' ([[International Nonproprietary Name|INN]]; brand names Equioxx and Previcox) is a [[non-steroidal anti-inflammatory drug]] of the [[COX-2 inhibitor]] (coxib) class, currently approved for use in dogs and horses. Firocoxib was the first COX-2 inhibitor approved by the U.S. [[Food and Drug Administration]] for horses.<ref>{{cite web | url = http://www.thehorse.com/ViewArticle.aspx?ID=9896 | title = New NSAID Equioxx (firocoxib) Approved by USEF | date = | {{SI}} | ||
{{CMG}} | |||
==Overview== | |||
'''Firocoxib''' ([[International Nonproprietary Name|INN]]; brand names '''Equioxx''' and '''Previcox''') is a [[non-steroidal anti-inflammatory drug]] of the [[COX-2 inhibitor]] (coxib) class, currently approved for use in dogs and horses. Firocoxib was the first COX-2 inhibitor approved by the U.S. [[Food and Drug Administration]] for horses.<ref>{{cite web | url = http://www.thehorse.com/ViewArticle.aspx?ID=9896 | title = New NSAID Equioxx (firocoxib) Approved by USEF | date = July 2, 2007 | accessdate = 2008-04-18 | work = The Horse}}</ref> Firocoxib is not intended or approved for use in human medicine.<ref>[http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Scientific_Discussion/veterinary/000142/WC500065936.pdf Equioxx], European Medicines Agency</ref> | |||
==References== | ==References== | ||
{{Reflist}} | {{Reflist|2}} | ||
{{NSAIDs}} | {{NSAIDs}} | ||
[[Category:Dog health]] | [[Category:Dog health]] | ||
[[Category:Lactones]] | [[Category:Lactones]] | ||
[[Category:Sulfones]] | [[Category:Sulfones]] | ||
[[Category:Non-steroidal anti-inflammatory drugs]] | |||
[[Category:Furans]] | |||
[[Category:Ethers]] | |||
[[Category:Drug]] |
Latest revision as of 15:57, 8 April 2015
Clinical data | |
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Trade names | Equioxx; Previcox |
AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral |
ATCvet code | |
Legal status | |
Legal status | |
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
Chemical and physical data | |
Formula | C17H20O5S |
Molar mass | 336.402 g/mol |
3D model (JSmol) | |
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(verify) |
WikiDoc Resources for Firocoxib |
Articles |
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Most recent articles on Firocoxib |
Media |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Firocoxib at Clinical Trials.gov Clinical Trials on Firocoxib at Google
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Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Firocoxib
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Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Firocoxib Discussion groups on Firocoxib Directions to Hospitals Treating Firocoxib Risk calculators and risk factors for Firocoxib
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Healthcare Provider Resources |
Causes & Risk Factors for Firocoxib |
Continuing Medical Education (CME) |
International |
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Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Firocoxib (INN; brand names Equioxx and Previcox) is a non-steroidal anti-inflammatory drug of the COX-2 inhibitor (coxib) class, currently approved for use in dogs and horses. Firocoxib was the first COX-2 inhibitor approved by the U.S. Food and Drug Administration for horses.[1] Firocoxib is not intended or approved for use in human medicine.[2]
References
- ↑ "New NSAID Equioxx (firocoxib) Approved by USEF". The Horse. July 2, 2007. Retrieved 2008-04-18.
- ↑ Equioxx, European Medicines Agency
- Pages with script errors
- Template:drugs.com link with non-standard subpage
- Drugs with non-standard legal status
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Chemical articles with unknown parameter in Infobox drug
- Chemical pages without DrugBank identifier
- Dog health
- Lactones
- Sulfones
- Non-steroidal anti-inflammatory drugs
- Furans
- Ethers
- Drug