Proglumetacin

Proglumetacin

Clinical data
ATC code	M01AB14 (WHO)
Pharmacokinetic data
Metabolism	Hepatic. Undergoes enterohepatic recirculation
Identifiers
IUPAC name 3-[4-[2-[2-[1-(4-chlorobenzoyl)-5-methoxy-2- methylindol-3-yl]acetyl]oxyethyl]piperazin-1-yl] propyl 4-(benzoylamino)-5-(dipropylamino)- 5-oxopentanoate
CAS Number	57132-53-3 59209-40-4 (maleate)
PubChem CID	4921
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C46H58ClN5O8
Molar mass	844.43442 g/mol

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Evidence Based Medicine
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Clinical Trials
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Guidelines / Policies / Govt
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Commentary
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Definitions
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Patient Resources / Community
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Healthcare Provider Resources
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Continuing Medical Education (CME)
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International
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Business
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Experimental / Informatics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Proglumetacin (usually as the maleate salt, trade names Afloxan, Protaxon and Proxil) is a non-steroidal anti-inflammatory drug. It is metabolized in the body to indometacin and proglumide, a drug with antisecretory effects that helps prevent injury to the stomach lining.