Breast cancer laboratory tests: Difference between revisions
Jump to navigation
Jump to search
(Mahshid) |
No edit summary |
||
| Line 1: | Line 1: | ||
__NOTOC__ | __NOTOC__ | ||
{{CMG}} {{AE}}{{MGS}}l; {{Ammu}} | {{CMG}} {{AE}}{{MGS}}l; {{Ammu}} | ||
{{Breast cancer}} | {{Breast cancer}} | ||
| Line 5: | Line 6: | ||
An elevated concentration of serum alkaline phosphatase is diagnostic of bone metastasis of breast cancer. | An elevated concentration of serum alkaline phosphatase is diagnostic of bone metastasis of breast cancer. | ||
==Blood Chemistry== | ==Blood Chemistry== | ||
Blood chemistry tests measure certain chemicals in the blood. They show how well certain organs are functioning and can also be used to detect abnormalities. They are used to stage breast cancer. <ref name = ss> Breast cancer. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/breast/signs-and-symptoms/?region=on#ixzz3xScycfqv Accessed on January 16, 2016</ref> | Blood chemistry tests measure certain chemicals in the blood. They show how well certain organs are functioning and can also be used to detect abnormalities. They are used to stage breast cancer. <ref name="ss">Breast cancer. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/breast/signs-and-symptoms/?region=on#ixzz3xScycfqv Accessed on January 16, 2016</ref> | ||
*Urea (blood urea nitrogen or BUN) and creatinine may be measured to check kidney function. Kidney function is checked before chemotherapy is given and may be rechecked during or after treatment. | *Urea (blood urea nitrogen or BUN) and creatinine may be measured to check kidney function. Kidney function is checked before chemotherapy is given and may be rechecked during or after treatment. | ||
*Alanine aminotransferase (ALT), aspartate transaminase (AST) and alkaline phosphatase may be measured to check liver function. | *Alanine aminotransferase (ALT), aspartate transaminase (AST) and alkaline phosphatase may be measured to check liver function. | ||
| Line 16: | Line 17: | ||
==HER2 Status Testing== | ==HER2 Status Testing== | ||
*ERBB2 is a gene that has changed (mutated) so it helps a tumour grow oncogene. It is more commonly known as HER2 (or HER2/neu). HER2 stands for human epidermal growth factor receptor 2.<ref name = ss> Breast cancer. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/breast/signs-and-symptoms/?region=on#ixzz3xScycfqv Accessed on January 16, 2016</ref> | *ERBB2 is a gene that has changed (mutated) so it helps a tumour grow oncogene. It is more commonly known as HER2 (or HER2/neu). HER2 stands for human epidermal growth factor receptor 2.<ref name="ss">Breast cancer. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/breast/signs-and-symptoms/?region=on#ixzz3xScycfqv Accessed on January 16, 2016</ref> | ||
*HER2 status testing is done to find out the amount of HER2 produced by a breast tumor. | *HER2 status testing is done to find out the amount of HER2 produced by a breast tumor. | ||
Other Genetic panels such as | |||
Ki-67 | |||
==References== | ==References== | ||
Revision as of 12:59, 2 April 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Mirdula Sharma, MBBS [2]l; Ammu Susheela, M.D. [3]
|
Breast Cancer Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Breast cancer laboratory tests On the Web |
|
American Roentgen Ray Society Images of Breast cancer laboratory tests |
|
Risk calculators and risk factors for Breast cancer laboratory tests |
Overview
An elevated concentration of serum alkaline phosphatase is diagnostic of bone metastasis of breast cancer.
Blood Chemistry
Blood chemistry tests measure certain chemicals in the blood. They show how well certain organs are functioning and can also be used to detect abnormalities. They are used to stage breast cancer. [1]
- Urea (blood urea nitrogen or BUN) and creatinine may be measured to check kidney function. Kidney function is checked before chemotherapy is given and may be rechecked during or after treatment.
- Alanine aminotransferase (ALT), aspartate transaminase (AST) and alkaline phosphatase may be measured to check liver function.
- Increased levels could indicate that cancer has spread to the liver.
- Alkaline phosphatase can also be used to check for cancer in the bone.
- Increased levels could indicate that cancer has spread to the bone.
BRCA1/BRCA 2 Gene Testing
Genetic markers, if present, suggest an 80% likelihood of breast cancer occurrence.
HER2 Status Testing
- ERBB2 is a gene that has changed (mutated) so it helps a tumour grow oncogene. It is more commonly known as HER2 (or HER2/neu). HER2 stands for human epidermal growth factor receptor 2.[1]
- HER2 status testing is done to find out the amount of HER2 produced by a breast tumor.
Other Genetic panels such as
Ki-67
References
- ↑ 1.0 1.1 Breast cancer. Canadian Cancer Society (2015) http://www.cancer.ca/en/cancer-information/cancer-type/breast/signs-and-symptoms/?region=on#ixzz3xScycfqv Accessed on January 16, 2016