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==Overview==
==Overview==
[[Epidemiological]] risk factors for a disease can provide important clues as to the [[etiology]] of a disease.  The first work on breast cancer epidemiology was done by [[Janet Lane-Claypon]], who published a comparative study in 1926 for the British Ministry of Health of 500 breast cancer cases and 500 control patients of the same background and lifestyle.{{Fact|date=June 2007}}  Although many epidemiological risk factors have been identified, the cause of any individual breast cancer is often unknown.  In other words, epidemiological research informs of the patterns of breast cancer incidence across certain populations, but not in a given individual.  Approximately 5% of new breast cancers are attributable to hereditary syndromes, while no [[etiology]] is known for the other 95% of cases.<ref name=Madigan_1995>{{cite journal | author = Madigan MP, Ziegler RG, Benichou J, Byrne C, Hoover RN | title = Proportion of breast cancer cases in the United States explained by well-established risk factors | journal = J. Natl. Cancer Inst. | volume = 87 | issue = 22 | pages = 1681-5 | year = 1995 | pmid = 7473816 | doi = | accessdate = 2007-05-26}}</ref>
The cause of breast cancer is not yet known exactly, though many risk factors can increase the chance of developing breast cancer.
 
==Causes==
=====Drug Side Effect=====
The cause of breast cancer is not yet known exactly, though many risk factors can increase the chance of developing breast cancer.<ref name="cause">Breast Cancer. American Cancer Society (2019) http://www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-what-causes Accessed on March 1 2019 </ref> [[BRCA1]] or [[BRCA2]] tumor suppressor genes and less commonly  [[PALB2]], [[ATM]] or [[CHEK2]] are among known genes that may increase the risk of developing breast cancer, nevertheless none of the above mentioned genes can cause developing breast cancer.<ref name="cause">Breast Cancer. American Cancer Society (2019) http://www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-what-causes Accessed on March 1 2019</ref>
 
[[Clomifene]], [[Desogestrel and Ethinyl Estradiol]], [[Medroxyprogesterone]], [[Norgestimate and Ethinyl estradiol]], [[Progesterone]], [[Spironolactone]]
 
==References==
==References==


{{Reflist|2}}
{{Reflist|2}}


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[[Category:Disease]]
[[Category:Disease]]
[[Category:Types of cancer]]
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[[Category:Hereditary cancers]]
[[Category:Hereditary cancers]]
[[Category:Mature chapter]]
[[Category:Mature chapter]]
[[Category:Oncology]]
[[Category:Up-To-Date]]
[[Category:Oncology]]
[[Category:Medicine]]
[[Category:Gynecology]]
[[Category:Surgery]]

Latest revision as of 22:52, 1 May 2019

Breast Cancer Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mirdula Sharma, MBBS [2] Soroush Seifirad, M.D.[3]

Overview

The cause of breast cancer is not yet known exactly, though many risk factors can increase the chance of developing breast cancer.

Causes

The cause of breast cancer is not yet known exactly, though many risk factors can increase the chance of developing breast cancer.[1] BRCA1 or BRCA2 tumor suppressor genes and less commonly PALB2, ATM or CHEK2 are among known genes that may increase the risk of developing breast cancer, nevertheless none of the above mentioned genes can cause developing breast cancer.[1]

References

  1. 1.0 1.1 Breast Cancer. American Cancer Society (2019) http://www.cancer.org/cancer/breastcancer/detailedguide/breast-cancer-what-causes Accessed on March 1 2019