Sandbox/cellulitis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mugilan Poongkunran M.B.B.S [2]

Cellulitis Microchapters

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Overview

Typically a combination of intravenous and oral antibiotics are administered for the treatment of cellulitis. Bed rest and elevation of the affected limbs are recommended to accompany the antibiotic treatment. In patients with edema of the extremities, compressive stockings may really aid in treating the fluid accumulation. Small abscesses surrounding the affected tissue can be treated with a simple incision and drainage of the fluid. It is advised to drink plenty of fluids during your treatment and recovery.

Medical Therapy

Empiric Therapy for Cellulitis in Neonates

▸ Click on the following categories to expand treatment regimens.

Preferred Regimen

  ▸  Infants 0 to 4 weeks of age

  ▸  Infants <1 week of age

  ▸  Infants ≥1 week of age

Infants 0 to 4 weeks of age
Parental Regimen
Vancomycin 15 mg/kg IV q24h
PLUS
Cefotaxime 50 mg/kg IV q12h
OR
Gentamicin 2.5 mg/kg IV q18-24h
Infants 0 to 4 weeks of age
Oral Regimen
Clindamycin 5 mg/kg orally q12h
OR
Linezolid 10 mg/kg orally q8-12h
Infants <1 week of age (BW 1200 to 2000 g)
Parental Regimen
Vancomycin 10 to 15 mg/kg IV q12-18h
PLUS
Cefotaxime 50 mg/kg IV q12h
OR
Gentamicin 2.5 mg/kg IV q12h
Infants <1 week of age (BW 1200 to 2000 g)
Oral Regimen
Clindamycin 5 mg/kg orally q12h
OR
Linezolid 10 mg/kg orally q8-12h
Infants <1 week of age (BW >2000 g)
Preferred Regimen
Vancomycin 10 to 15 mg/kg IV q8-12h
PLUS
Cefotaxime 50 mg/kg IV q8-12h
OR
Gentamicin 2.5 mg/kg IV q12h
Infants 0 to 4 weeks of age
Preferred Regimen
Clindamycin 5 mg/kg orally q8h
OR
Linezolid 10 mg/kg orally q8-12h
Infants ≥1 week of age (BW 1200 to 2000 g)
Preferred Regimen
Vancomycin 10 to 15 mg/kg IV q8-12h
PLUS
Cefotaxime 50 mg/kg IV q8h
OR
Gentamicin 2.5 mg/kg IV q8-12h
Infants ≥1 week of age (BW > 2000 g)
Preferred Regimen
Vancomycin 10 to 15 mg/kg IV q6-8h
PLUS
Cefotaxime 50 mg/kg IV q6-8h
OR
Gentamicin 2.5 mg/kg IV q8h
Infants 0 to 4 weeks of age
Preferred Regimen
Clindamycin 5 mg/kg orally q8h
OR
Linezolid 10 mg/kg orally q8h
Infants 0 to 4 weeks of age
Preferred Regimen
Clindamycin 5 mg/kg orally q6h
OR
Linezolid 10 mg/kg orally q8h

References


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