Cancer of unknown primary origin history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: ; Roukoz A. Karam, M.D.[2]

Overview

The majority of patients with cancer of unknown primary origin are asymptomatic.

History and Symptoms

The majority of patients with cancer of unknown primary origin are asymptomatic.[1]

The hallmark of CUP is determined by the specific metastatic sites involved, which are usually more than one at time of diagnosis.

Patients often present with signs and symptoms related to the sites involved including the liver, lungs, lymph nodes, and bones.

Common Symptoms

Common symptoms of cancer of unknown primary origin may include the following:[1]

Less Common Symptoms

Less common symptoms of cancer of unknown primary origin may include the following:[1]

References

  1. 1.0 1.1 1.2 Varadhachary GR (2007). "Carcinoma of unknown primary origin". Gastrointest Cancer Res. 1 (6): 229–35. PMC 2631214. PMID 19262901.