Cancer of unknown primary origin classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: , Roukoz A. Karam, M.D.[2]
Overview
Cancer of unknown primary origin may be classified based on light microscopy of the tissue biopsy into 4 groups including adenocarcinomas, squamous cell carcinomas, poorly differentiated tumors, and carcinomas with neuroendocrine differentiation.
Classification
Cancer of unknown primary origin may be classified based on light microscopy of the tissue biopsy into 4 main groups:[1]
- Well or moderately differentiated adenocarcinomas
- Poorly differentiated or undifferentiated adenocarcinoma
- Squamous cell carcinomas
- Poorly differentiated tumors
- Carcinomas with neuroendocrine differentiation