Tumor lysis syndrome causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Nazia Fuad M.D.
Overview
Development of tumor lysis syndrome is the result of initiation of chemotherapy or radiotherapy in cancer patients and sometimes even without treatment.
Causes
Common Causes
- Burkitt's lymphoma
- Acute lymphoblastic leukemia
- Acute myeloid leukemia
- Chemotherapy including methotrexate
Causes by Organ System
Cardiovascular | No underlying causes |
Chemical/Poisoning | No underlying causes |
Dental | No underlying causes |
Dermatologic | No underlying causes |
Drug Side Effect |
Bortezomib, Carfilzomib, Cytarabine, cytotoxic chemotherapy, Doxorubicin Hydrochloride etoposide, fludarabine, glucocorticoids, hydroxyurea, Ibrutinib, imatinib, lenalidomide , Nelarabine, Nilotinib, Ofatumumab, paclitaxel, Pralatrexate, rituximab, thalidomide, Vincristine sulfate liposome zoledronic acid |
Ear Nose Throat | No underlying causes |
Endocrine | No underlying causes |
Environmental | No underlying causes |
Gastroenterologic | No underlying causes |
Genetic | No underlying causes |
Hematologic | No underlying causes |
Iatrogenic | No underlying causes |
Infectious Disease | No underlying causes |
Musculoskeletal/Orthopedic | No underlying causes |
Neurologic | No underlying causes |
Nutritional/Metabolic | No underlying causes |
Obstetric/Gynecologic | No underlying causes |
Oncologic |
Acute lymphoblastic leukemia , acute myeloid leukemia, adult T-cell leukemia/lymphoma , anaplastic large cell lymphoma, breast cancer , Burkitt's lymphoma, chronic myeloid leukemia, diffuse large B-cell lymphoma, gastrointestinal stromal tumors, germ cell tumors , hepatoblastoma, hepatocellular carcinoma, hodgkin's disease, isolated plasmacytomas, mantle cell lymphoma, medulloblastoma, melanoma, metastatic colorectal cancer , multiple myeloma, neuroblastoma, Non-Hodgkin lymphoma, ovarian cancer , rhabdomyosarcoma, sarcoma, small cell lung cancer, squamous cell carcinoma of the vulva, thalidomide, transformed lymphoma, urothelial cancer |
Ophthalmologic | No underlying causes |
Overdose/Toxicity | |
Psychiatric | No underlying causes |
Pulmonary | No underlying causes |
Renal/Electrolyte | |
Rheumatology/Immunology/Allergy |
No underlying causes|- |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | No underlying causes |