Sandbox: wdx causes

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Intestinal adaptation
Phase Duration Main feature Management
Therapy Measurement
Acute phase 1 to 3 months
  • Aggressive fluid and electrolyte replacement 
  • Cyclical parenteral nutrition (overnight feeding)
  •  Intravenous administration of proton pump inhibitors or H2 receptor blockers
  • Prophylactic oral antibiotics such as neomycin and metronidazole
  • Prophylaxis with cholecystokinin
  • Administration percutaneous central venous catheter
  • Frequent measurements of vital signs, intake and output, and central venous pressures  
Adaptive phase 1 to 2 years
  • Reaching 90% to 95% of the bowel adaptation potential
  • Enterocyte and villous hyperplasia
  • Increased mucosal surface area
  • Converting unabsorbed carbohydrates into absorbable short-chain fatty acids
  • Gaining weight
  • Stabilization of fluid and electrolyte levels
  • Total parenteral nutrition
  • Initiating enteral feeding 
  • Adding trophic factors
Maintenance phase
  • Reaching the maximum bowel adaptation potential
  • Individualized permanent nutrition treatment
  • Oral nutrition