Sheehan's syndrome natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

  • Sheehan syndrome, if left untreated lead to mitral regurgitation, pericardial effusion and diminished LVM.[1]
  • Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
  • Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.

Natural History, Complications, and Prognosis

Natural History

  • The symptoms of Sheehan's syndrome can develop during immediate post-puerperal period to years after delivery.
  • If left untreated,lead to mitral regurgitation, pericardial effusion and diminished LVM, adrenal crisis, pituitay hypopituitarism and empty sella syndrome.

Complications

  • Common complications of [disease name] include:
    • Adrenal crisis
    • Hypotension
    • Hypothyroidism
    • Menstrual irregularities
    • Empty sella syndrome

Prognosis

  • Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [#]%.
  • Depending on the extent of the [tumor/disease progression/etc.] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
  • The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
  • [Subtype of disease/malignancy] is associated with the most favorable prognosis.
  • The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.

References

  1. Laway BA, Ramzan M, Allai MS, Wani AI, Misgar RA (2016). "CARDIAC STRUCTURAL AND FUNCTIONAL ABNORMALITIES IN FEMALES WITH UNTREATED HYPOPITUITARISM DUE TO SHEEHAN SYNDROME: RESPONSE TO HORMONE REPLACEMENT THERAPY". Endocr Pract. 22 (9): 1096–103. doi:10.4158/EP161262.OR. PMID 27359291.

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