Gliomatosis cerebri medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2]

Overview

The predominant therapy for gliomatosis cerebri is surgical resection. Adjunctive chemotherapy and radiation may be required. Supportive therapy for gliomatosis cerebri includes anticonvulsants and corticosteroids.

Medical Therapy

The predominant therapy for gliomatosis cerebri is surgical resection. Adjunctive chemotherapy and radiation may be required. Supportive therapy for gliomatosis cerebri includes anticonvulsants and corticosteroids.

Radiotherapy

  • Post-operative radiotherapy is recommended among all patients who develop gliomatosis cerebri.
  • Radiotherapy may not cure the cancer, but can control the tumor and delay recurrence.
  • Targeted three-dimensional conformal radiotherapy is preferred to whole brain radiotherapy.
  • The median dose of radiation is 55.4 Gy (range, 45–61.2 Gy).

Chemotherapy

Supportive treatment

Supportive therapy for gliomatosis cerebri includes anticonvulsants and corticosteroids, which focuses on relieving symptoms and improving the patient’s neurologic function.

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