Adrenal atrophy history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maryam Hadipour, M.D.[2]

Overview

The most common signs and symptoms of adrenal atrophy are fatigue, weight loss, salt craving, abdominal pain and myalgia.

History and Symptoms

The symptoms and signs of adrenal insufficiency depend upon the rate and extent of loss of adrenal function, whether mineralocorticoid production is preserved, and the degree of stress. The onset of adrenal insufficiency is often very gradual, and it may go undetected until an illness or other stress precipitates adrenal crisis. However, the most common symptoms in patients with adrenal atrophy are as follows:

References

  1. Abdu TA, Elhadd TA, Neary R, Clayton RN (March 1999). "Comparison of the low dose short synacthen test (1 microg), the conventional dose short synacthen test (250 microg), and the insulin tolerance test for assessment of the hypothalamo-pituitary-adrenal axis in patients with pituitary disease". J Clin Endocrinol Metab. 84 (3): 838–43. doi:10.1210/jcem.84.3.5535. PMID 10084558.
  2. Husebye ES, Perheentupa J, Rautemaa R, Kämpe O (May 2009). "Clinical manifestations and management of patients with autoimmune polyendocrine syndrome type I". J Intern Med. 265 (5): 514–29. doi:10.1111/j.1365-2796.2009.02090.x. PMID 19382991.

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