Measles medical therapy: Difference between revisions
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==Medical Therapy== | ==Medical Therapy== | ||
According to current data, there is no [[Antiviral | According to current data, there is no [[Antiviral Therapy|antiviral therapy]] for [[measles]] [[infection]] and standard treatment is focused on supportive care. Yet, case reports have noted the ''in vitro'' susceptibility of [[measles virus]] to [[ribavirin]]. [[Ribavirin]], in parallel with other [[drugs]], such as [[interferon-α]] have been used in more severe cases of [[measles]], specially when in the presence of [[CNS infection]].<ref name="MossGriffin2012">{{cite journal|last1=Moss|first1=William J|last2=Griffin|first2=Diane E|title=Measles|journal=The Lancet|volume=379|issue=9811|year=2012|pages=153–164|issn=01406736|doi=10.1016/S0140-6736(10)62352-5}}</ref><ref name="pmid20390298">{{cite journal| author=Reuter D, Schneider-Schaulies J| title=Measles virus infection of the CNS: human disease, animal models, and approaches to therapy. | journal=Med Microbiol Immunol | year= 2010 | volume= 199 | issue= 3 | pages= 261-71 | pmid=20390298 | doi=10.1007/s00430-010-0153-2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20390298 }} </ref> | ||
==References== | ==References== | ||
Revision as of 15:42, 24 June 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Despite the efforts made in the past years to develop a treatment regimen for measles, there is still no specific antiviral therapy for uncomplicated cases of measles, however, some drugs such as ribavirin and interferon-α have been used in the more severe cases of the condition, notably for cases of infection of the CNS by the virus. Yet, there is evidence that the administration of two doses of vitamin A in children, under the age of two, was associated with a reduced risk of morbidity and mortality from the disease. For most patients with measles, the standard treatment is focused on supportive care.[1][2][3]
Medical Therapy
According to current data, there is no antiviral therapy for measles infection and standard treatment is focused on supportive care. Yet, case reports have noted the in vitro susceptibility of measles virus to ribavirin. Ribavirin, in parallel with other drugs, such as interferon-α have been used in more severe cases of measles, specially when in the presence of CNS infection.[1][3]
References
- ↑ 1.0 1.1 Moss, William J; Griffin, Diane E (2012). "Measles". The Lancet. 379 (9811): 153–164. doi:10.1016/S0140-6736(10)62352-5. ISSN 0140-6736.
- ↑ Huiming Y, Chaomin W, Meng M (2005). "Vitamin A for treating measles in children". Cochrane Database Syst Rev (4): CD001479. doi:10.1002/14651858.CD001479.pub3. PMID 16235283.
- ↑ 3.0 3.1 Reuter D, Schneider-Schaulies J (2010). "Measles virus infection of the CNS: human disease, animal models, and approaches to therapy". Med Microbiol Immunol. 199 (3): 261–71. doi:10.1007/s00430-010-0153-2. PMID 20390298.