Pleomorphic adenoma: Difference between revisions

Jump to navigation Jump to search
Line 29: Line 29:


==[[Pleomorphic adenoma other diagnostic studies|Other Diagnostic Studies]]==
==[[Pleomorphic adenoma other diagnostic studies|Other Diagnostic Studies]]==
 
In terms of imaging studies, ultrasound can determine and characterize superficial parotid tumors. Certain types of salivary gland tumors have certain sonographic characteristics on ultrasound<ref>{{cite journal |author=Białek EJ, Jakubowski W, Karpińska G |title=Role of ultrasonography in diagnosis and differentiation of pleomorphic adenomas: work in progress |journal=Arch Otolaryngol Head Neck Surg |volume=129 |issue=9 |pages=929–33 |year=2003 |month=Sep |pmid=12975263 |doi=10.1001/archotol.129.9.929 |url=}}</ref>. Ultrasound is also frequently used to guide FNA or core needle biopsy.  CT allows direct, bilateral visualization of the salivary gland tumor and provides information about overall dimension and tissue invasion. CT is excellent for demonstrating bony invasion. MRI provides superior soft tissue delineation such as perineural invasion when compared to CT only<ref>{{cite journal |author=Koyuncu M, Seşen T, Akan H, ''et al'' |title=Comparison of computed tomography and magnetic resonance imaging in the diagnosis of parotid tumors |journal=Otolaryngol Head Neck Surg |volume=129 |issue=6 |pages=726–32 |year=2003 |month=Dec |pmid=14663442 |doi=10.1016/j.otohns.2003.07.009 |url=}}</ref>.
 
The diagnosis of salivary gland tumors utilize both histopathological sampling and radiographic studies. Histopathological sampling procedures include [[fine needle aspiration]] (FNA) and core needle biopsy (bigger needle comparing to FNA). Both of these procedures can be done in an outpatient setting.  Diagnostic imaging techniques for salivary gland tumors include [[ultrasound]], [[computer tomography]] (CT) and [[magnetic resonance imaging]] (MRI).  Fine needle aspiration biopsy (FNA), operated in experienced hands, can determine whether the tumor is malignant in nature with [[sensitivity]] around 90%<ref>{{cite journal |author=Cohen EG, Patel SG, Lin O, ''et al'' |title=Fine-needle aspiration biopsy of salivary gland lesions in a selected patient population |journal=Arch Otolaryngol Head Neck Surg |volume=130 |issue=6 |pages=773–8 |year=2004 |month=Jun |pmid=15210562 |doi=10.1001/archotol.130.6.773 |url=}}</ref><ref>{{cite journal |author=Batsakis JG, Sneige N, el-Naggar AK |title=Fine-needle aspiration of salivary glands: its utility and tissue effects |journal=Ann Otol Rhinol Laryngol |volume=101 |issue=2 Pt 1 |pages=185–8 |year=1992 |month=Feb |pmid=1739267 |doi= |url=}}</ref>. FNA can also distinguish primary salivary tumor from metastatic disease.  Core needle biopsy can also be done in outpatient setting. It is more invasive but is more accurate compared to FNA with diagnostic [[accuracy]] greater than 97%<ref>{{cite journal |author=Wan YL, Chan SC, Chen YL, ''et al'' |title=Ultrasonography-guided core-needle biopsy of parotid gland masses |journal=AJNR Am J Neuroradiol |volume=25 |issue=9 |pages=1608–12 |year=2004 |month=Oct |pmid=15502149 |doi= |url=http://www.ajnr.org/cgi/pmidlookup?view=long&pmid=15502149}}</ref>. Furthermore, core needle biopsy allows more accurate histological typing of the tumor.  In terms of imaging studies, ultrasound can determine and characterize superficial parotid tumors. Certain types of salivary gland tumors have certain sonographic characteristics on ultrasound<ref>{{cite journal |author=Białek EJ, Jakubowski W, Karpińska G |title=Role of ultrasonography in diagnosis and differentiation of pleomorphic adenomas: work in progress |journal=Arch Otolaryngol Head Neck Surg |volume=129 |issue=9 |pages=929–33 |year=2003 |month=Sep |pmid=12975263 |doi=10.1001/archotol.129.9.929 |url=}}</ref>. Ultrasound is also frequently used to guide FNA or core needle biopsy.  CT allows direct, bilateral visualization of the salivary gland tumor and provides information about overall dimension and tissue invasion. CT is excellent for demonstrating bony invasion. MRI provides superior soft tissue delineation such as perineural invasion when compared to CT only<ref>{{cite journal |author=Koyuncu M, Seşen T, Akan H, ''et al'' |title=Comparison of computed tomography and magnetic resonance imaging in the diagnosis of parotid tumors |journal=Otolaryngol Head Neck Surg |volume=129 |issue=6 |pages=726–32 |year=2003 |month=Dec |pmid=14663442 |doi=10.1016/j.otohns.2003.07.009 |url=}}</ref>.


==[[Pleomorphic adenoma pathophysiology|Pathophysiology]]==
==[[Pleomorphic adenoma pathophysiology|Pathophysiology]]==

Revision as of 15:31, 21 January 2012

Template:DiseaseDisorder infobox

Pleomorphic adenoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Pleomorphic adenoma from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

CT scan

MRI

Echocardiography and Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Pleomorphic adenoma On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Pleomorphic adenoma

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Pleomorphic adenoma

CDC on Pleomorphic adenoma

Pleomorphic adenoma in the news

Blogs on Pleomorphic adenoma

Directions to Hospitals Treating Pleomorphic adenoma

Risk calculators and risk factors for Pleomorphic adenoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Cafer Zorkun M.D., PhD.

Overview

History & Symptoms

Diagnosis

MRI

CT

Echocardiography or Ultrasound

Other Diagnostic Studies

In terms of imaging studies, ultrasound can determine and characterize superficial parotid tumors. Certain types of salivary gland tumors have certain sonographic characteristics on ultrasound[1]. Ultrasound is also frequently used to guide FNA or core needle biopsy. CT allows direct, bilateral visualization of the salivary gland tumor and provides information about overall dimension and tissue invasion. CT is excellent for demonstrating bony invasion. MRI provides superior soft tissue delineation such as perineural invasion when compared to CT only[2].

Pathophysiology

Treatment

Surgery

References

  1. Białek EJ, Jakubowski W, Karpińska G (2003). "Role of ultrasonography in diagnosis and differentiation of pleomorphic adenomas: work in progress". Arch Otolaryngol Head Neck Surg. 129 (9): 929–33. doi:10.1001/archotol.129.9.929. PMID 12975263. Unknown parameter |month= ignored (help)
  2. Koyuncu M, Seşen T, Akan H; et al. (2003). "Comparison of computed tomography and magnetic resonance imaging in the diagnosis of parotid tumors". Otolaryngol Head Neck Surg. 129 (6): 726–32. doi:10.1016/j.otohns.2003.07.009. PMID 14663442. Unknown parameter |month= ignored (help)

See also

External links



Template:WikiDoc Sources