Squamous cell carcinoma of the skin laboratory findings: Difference between revisions

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{{CMG}}; '''Associate Editor(s)-in-Chief:''' [[User:Aditya Govindavarjhulla|Aditya Govindavarjhulla, M.B.B.S.]] [mailto:agovi@wikidoc.org], [[User:Raviteja Reddy Guddeti|Raviteja Guddeti, M.B.B.S.]] [mailto:ravitheja.g@gmail.com]
{{CMG}}; '''Associate Editor(s)-in-Chief:''' [[User:Aditya Govindavarjhulla|Aditya Govindavarjhulla, M.B.B.S.]] [mailto:agovi@wikidoc.org], [[User:Raviteja Reddy Guddeti|Raviteja Guddeti, M.B.B.S.]] [mailto:ravitheja.g@gmail.com]
== Overview ==
== Overview ==
Squamous cell carcinoma of the skin is most often caused by long term exposure to the sun, and other certain risk factors. No specific laboratory tests are indicated for the diagnosis, as physical exam and biopsy are the primary means of diagnosis. Histopathological evaluation of the biopsy specimen stands out to be the most important diagnostic test.
[[Squamous cell carcinoma of the skin]] is most often caused by long term exposure to the sun, and other certain [[risk factors]]. No specific laboratory tests are indicated for the [[diagnosis]], as [[physical exam]] and [[biopsy]] are the primary means of [[diagnosis]]. [[Histopathological|Histopathological evaluation]] of the [[biopsy]] specimen stands out to be the most important [[diagnostic]] [[Test|test.]]


== Laboratory Findings ==
== Laboratory Findings ==
* No specific [[laboratory]] [[Test|tests]] are required for the [[diagnosis]] of [[Squamous cell carcinoma of skin|squamous cell carcinoma]]. Routine [[blood tests]] are performed as part of the complete evaluation, including a [[Complete blood counts|complete blood count]] and [[Electrolyte|serum electrolytes]].


No specific laboratory tests are required for the diagnosis of squamous cell carcinoma. Routine blood tests are performed as part of the complete evaluation, including a complete blood count and serum electrolytes. Liver function tests will help to determine if there is metastatic spread to the liver. Blood gas analysis and pulmonary function testing may be helpful in cases of SCC of lungs, in addition to other imaging studies. Another important test to assess for [[paraneoplastic syndrome]] is a serum calcium, as SCC of the lungs can cause [[hypercalcemia]]. For this reason, blood levels of [[parathormone]] should also be obtained if SCC of the lung is suspected.
* [[Liver function tests]] will help to determine if there is [[metastatic]] spread to the [[liver]].  
* [[Blood gas analysis]] and [[pulmonary function testing]] may be helpful in cases of [[Squamous cell carcinoma of lung|Squamous cell carcinoma of lungs]], in addition to other [[imaging studies]].  
* Another important test to assess for [[paraneoplastic syndrome]] is a [[Calcium|serum calcium]], (as [[Squamous cell carcinoma of the lung|Squamos cell carcinoma of the lungs]] can cause [[hypercalcemia]]) and [[Parathyroid hormone|serum parathyroid hormones leve]]<nowiki/>l.
'''<u>Sputum Cytology</u>'''
* [[Squamous cell carcinoma of lung|SCC of the lung w]]<nowiki/>hich is centrally located and exfoliates, will secrete [[Cells (biology)|cells]] that can be visualized on [[sputum]] [[cytology]].


'''<u>Sputum Cytology</u>'''
* Although sputum cytology is fast, easy, and economical it has a high false negative rate, and accuracy is highly dependent on storage, collection, number of samples, and the location of the [[tumor]]
SCC of the lung which is centrally located and exfoliates, will secrete cells that can be visualized on sputum cytology. Although sputum cytology is fast, easy, and economical it has a high false negative rate, and accuracy is highly dependent on storage, collection, number of samples, and the location of the tumor.It is easy,quick and economical. Further analysis may be needed by obtaining biopsy samples during bronchoscopy.
 
* Further analysis may be needed by obtaining [[biopsy]] samples during [[bronchoscopy]].


==References==
==References==

Latest revision as of 17:29, 30 May 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2], Raviteja Guddeti, M.B.B.S. [3]

Overview

Squamous cell carcinoma of the skin is most often caused by long term exposure to the sun, and other certain risk factors. No specific laboratory tests are indicated for the diagnosis, as physical exam and biopsy are the primary means of diagnosis. Histopathological evaluation of the biopsy specimen stands out to be the most important diagnostic test.

Laboratory Findings

Sputum Cytology

  • Although sputum cytology is fast, easy, and economical it has a high false negative rate, and accuracy is highly dependent on storage, collection, number of samples, and the location of the tumor

References


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