Cytomegalovirus infection differential diagnosis: Difference between revisions

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Revision as of 15:11, 16 May 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S [2]

Overview

Differential Diagnosis of Cytomegalovirus infection

Cytomegalovirus Retinitis

Cytomegalovirus retinitis must be differentiated from the following infectious causes of retinitis:

Infectious Agent	Clinical Manifestations
Cytomegalovirus	Physical evidence of a cytomegalovirus presence in one of both eyes will generally clinical present in the form of lesions, adjacent retinal vessels. These lesions may impinge upon the fovea and the optic nerve. Furthermore they are usually discovered in close proximity to both. Further extending lesions may be present in close proximity to the vortex veins as well as the ora serrata.^[1]
Tuberculosis	Caseating granulomas Multiple choroidal tubercles- small grayish nodules located on the posterior pole of the eye Yellow necrotizing granulomas^[1]\|
Fungal	Candida albicans Visibly hazy vitreous White circumscribed lesions^[1] Aspergillus fumigatus Yellow subretinal infiltrates Retinal infiltrates Fungal hyphae are located throughout the eye - suggestive of pulmonary involvement^[1] Cryptococcus neoformans Yellowish-white lesions located on the fundus of the eye Mutton-fat keratic precipitates^[1]
Toxoplasmosis	Localized areas of infiltrate Active lesions are adjacent to initial scarring^[1]
Syphilis	Hemorrhagic areas Flare visible in anterior and posterior portions^[1]

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016.

[ret_phys-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016.

[1]

@@ Line 4: / Line 4: @@
 ==Overview==
+==Differential Diagnosis of Cytomegalovirus infection==
+===Cytomegalovirus Retinitis===
+Cytomegalovirus retinitis must be differentiated from the following infectious causes of retinitis:
+{| style="font-size: 85%;"
+! style="width: 80px; background: #4479BA; text-align: center;" |{{fontcolor|#FFF| Infectious Agent}}
+! style="width: 720px; background: #4479BA; text-align: center;" | {{fontcolor|#FFF|Clinical Manifestations}}
+|-
+| style="background: #F5F5F5; padding: 5px; text-align: center;" | Cytomegalovirus
+| style="background: #DCDCDC; padding: 5px;" |
+*Physical evidence of a [[Cytomegalovirus (patient information)|cytomegalovirus]] presence in one of both eyes will generally clinical present in the form of [[lesions]], adjacent retinal vessels.
+*These [[lesions]] may impinge upon the [[fovea]] and the [[optic nerve]]. Furthermore they are usually discovered in close proximity to both.
+*Further extending lesions may be present in close proximity to the vortex veins as well as the [[ora serrata]].<ref name="ret phys">Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016. </ref>
+|-
+| style="background: #F5F5F5; padding: 5px; text-align: center;" |Tuberculosis
+| style="background: #DCDCDC; padding: 5px;" |
+*Caseating [[Granuloma|granulomas]]
+*Multiple [[choroidal]] tubercles- small grayish nodules located on the posterior pole of the eye
+*Yellow [[necrotizing]] [[granulomas]]<ref name="ret phys">Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016. </ref>|
+|-
+| style="background: #F5F5F5; padding: 5px; text-align: center;" |Fungal
+| style="background: #DCDCDC; padding: 5px;" |
+====''Candida albicans''====
+*Visibly hazy [[Vitreous floaters|vitreous]]
+*White circumscribed [[lesions]]<ref name="ret phys">Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016. </ref>
+====''Aspergillus fumigatus''====
+*Yellow subretinal infiltrates
+*Retinal infiltrates
+*Fungal [[hyphae]] are located throughout the eye - suggestive of pulmonary involvement<ref name="ret phys">Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016. </ref>
+====''Cryptococcus neoformans''====
+*Yellowish-white lesions located on the [[fundus]] of the eye
+*Mutton-fat keratic [[precipitates]]<ref name="ret phys">Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016. </ref>
+|-
+| style="background: #F5F5F5; padding: 5px; text-align: center;" |Toxoplasmosis
+| style="background: #DCDCDC; padding: 5px;" |
+*Localized areas of infiltrate
+*Active [[lesions]] are adjacent to initial scarring<ref name="ret phys">Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016. </ref>
+|-
+| style="background: #F5F5F5; padding: 5px; text-align: center;" |Syphilis
+| style="background: #DCDCDC; padding: 5px;" |
+*[[Hemorrhagic]] areas
+*Flare visible in anterior and posterior portions<ref name="ret phys">Infectious Retinitis: A Review. YACHNA AHUJA, MD · STEVEN M. COUCH, MD · RAYMUND R. RAZONABLE, MD · SOPHIE J. BAKRI, MD. http://www.retinalphysician.com/articleviewer.aspx?articleID=102293. Accessed April 13, 2016. </ref>
+|-
+|}

Cytomegalovirus infection differential diagnosis: Difference between revisions

Revision as of 15:11, 16 May 2017

Overview

Differential Diagnosis of Cytomegalovirus infection

Cytomegalovirus Retinitis

Candida albicans

Aspergillus fumigatus

Cryptococcus neoformans

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