Oral candidiasis pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
[[Candida]] is a normal [[commensal]] of the skin and mucous membranes. The balance between the [[virulence]] of the [[fungus]] and the [[Immune response|host immune defense]] is responsible avoiding [[opportunistic infection]] of candida. | |||
Deficiency of [[cell-mediated immunity]] or poor general status are the main risk factors for having opportunistic candidiasis. | |||
Candidiasis is usually localized to skin and mucous membranes. In rare cases, candidiasis can spread causing [[Candidiasis|candidaemia]] and distant infection. These cases are usually associated with [[Immunodeficiency|deficient immunity]] | |||
[[C. albicans]] is the main species causing infection in humans more than any other candida species. | |||
==Pathophysiology== | ==Pathophysiology== | ||
===Gross Pathology=== | ===Gross Pathology=== |
Revision as of 13:06, 4 May 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Candida is a normal commensal of the skin and mucous membranes. The balance between the virulence of the fungus and the host immune defense is responsible avoiding opportunistic infection of candida. Deficiency of cell-mediated immunity or poor general status are the main risk factors for having opportunistic candidiasis. Candidiasis is usually localized to skin and mucous membranes. In rare cases, candidiasis can spread causing candidaemia and distant infection. These cases are usually associated with deficient immunity C. albicans is the main species causing infection in humans more than any other candida species.
Pathophysiology
Gross Pathology
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Oral manifestations of HIV infection and AIDS. Chronic oral candidiasis in patient with AIDS. Image courtesy of Professor Peter Anderson DVM PhD and published with permission. © PEIR, University of Alabama at Birmingham, Department of Pathology
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Soft palate showing extensive oral candidiasis in patient with AIDS. Image courtesy of Professor Peter Anderson DVM PhD and published with permission. © PEIR, University of Alabama at Birmingham, Department of Pathology
Videos
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