Pott's disease differential diagnosis: Difference between revisions

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!Imaging Findings
!Imaging Findings
|-
|-
|Pyogenic Abscess
|[[Pyogenic abscess]] of the [[spine]]
of the spine  
|Any age
|Any age
|Lumbar
|Lumbar spine
|Systemic illnesses like diabetes mellitus
|[[Diabetes mellitus]]
|Fever and marked back pain, myelopathy
|
|Elevated ESR  
*Fever  
Elevated WBC's
*[[Back pain]]
 
*[[Myelopathy]]
Elevated CRP
|
|Destruction of vertebral bodies and disc spaces, marked enhancement of the lesion, epidural abscess
*Elevated [[ESR]]
*Elevated [[WBC]]'s
*Elevated [[CRP]]
|
*Destruction of [[vertebra|vertebral]] bodies and disc spaces
*Enhancement of the lesion
*[[Epidural abscess]]
|-
|-
|Pott's Disease
|Pott's Disease
|Children and adults
|Children and adults
|Lumbo-thoracic
|Lumbo-thoracic
|Exposure to tuberculous infection
|Exposure to [[tuberculous infection]]
|Fever, malaise and weight loss, backache, myelopathy
|
|Elevated ESR  
*[[Fever]]
Normal WBC
*[[Malaise]]
|Destruction of vertebral bodies and disc spaces, rim enhancement of the soft-tissue masses
*[[Weight loss]]
*[[Backache]]
*[[Myelopathy]]
|
*Elevated [[ESR]]
*Normal [[WBC]]
|
*Destruction of vertebral bodies and disc spaces
*Rim enhancement of the soft-tissue masses
|-
|-
|Brucella abscess
|Brucellar abscess of the spine
of the spine
|Adults
|Adults
|Lumbar
|Lumbar
|Ingestion of unpasteurized milk
|Ingestion of unpasteurized milk
|Fever, malaise, weight loss, backache
|
|Elevated ESR  
*[[Fever]]
Elevated WBC
*[[Malaise]]
 
*[[Weight loss]]
Elevated CRP
*[[Backache]]
|Intact vertebral architecture despite diffuse vertebral osteomyelitis
|
*Elevated [[ESR]]
*Elevated [[WBC]]
*Elevated [[CRP]]
|
*Intact vertebral architecture even in the presence of diffuse vertebral [[osteomyelitis]]
|-
|-
|Vertebral Metastasis
|Vertebral [[Metastasis]]
|Elderly
|Elderly
|Thoracic
|Thoracic
|Presence of systemic malignancy
|Presence of systemic [[malignancy]]
|Bone pain at night, backache, back pain followed by radicular pain, myelopathy
|
|Normal WBC, ESR and CRP
*[[Bone pain]] at night
|Low signal intensity on T1-weighted images, hypersignal on T2-weighted images and heterogeneous enhancement
*[[Backache]]
*[[Radicular pain]]
*[[Myelopathy]]
|
*Normal [[WBC]]
*Normal [[ESR]]
*Normal [[CRP]]
|
*Low signal intensity on T1-weighted images
*Hypersignal on T2-weighted
*Heterogeneous enhancement
|}
|}
*[[Spinal tumor]]s
*[[Spinal tumor]]s

Revision as of 18:25, 28 March 2017

Pott's disease Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Hardik Patel, M.D.

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Overview

Pott's disease resembles spinal tumors, spinal cord abscess, Mycobacterium kansasii, nocardiosis, septic arthritis, metastatic cancer, multiple myeloma, miliary tuberculosis, spinal fungal infections, and Mycobacterium avium-intracellulare and needs to be differentiated from them.

Differentiating Pott's Disease from other Diseases

Pott's disease resembles the following disorders and needs to be differentiated from them:

Disease Age of Presentation Common site involved Risk Factors Clinical Features Laboratory Findings Imaging Findings
Pyogenic abscess of the spine Any age Lumbar spine Diabetes mellitus
Pott's Disease Children and adults Lumbo-thoracic Exposure to tuberculous infection
  • Destruction of vertebral bodies and disc spaces
  • Rim enhancement of the soft-tissue masses
Brucellar abscess of the spine Adults Lumbar Ingestion of unpasteurized milk
  • Intact vertebral architecture even in the presence of diffuse vertebral osteomyelitis
Vertebral Metastasis Elderly Thoracic Presence of systemic malignancy
  • Low signal intensity on T1-weighted images
  • Hypersignal on T2-weighted
  • Heterogeneous enhancement

References

  1. Mittal S, Khalid M, Sabir AB, Khalid S (2016). "Comparison of Magnetic Resonance Imaging Findings between Pathologically Proven Cases of Atypical Tubercular Spine and Tumour Metastasis: A Retrospective Study in 40 Patients". Asian Spine J. 10 (4): 734–43. doi:10.4184/asj.2016.10.4.734. PMC 4995258. PMID 27559455.

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