Sandbox ID Skin and Soft Tissues

• Bite infections

• Animal bite
• Preferred regimen (1): Amoxicillin-clavulanate 875/125 mg PO bid (Some gram-negative rods are resistant; misses MRSA)
• Preferred regimen (2): Ampicillin-sulbactam 1.5–3.0 g IV every 6–8 h (Some gram-negative rods are resistant; misses MRSA)

• Human bite

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• Cutaneous Anthrax

• Preferred regimen (1): (Penicillin Voral 500 mg 4 times daily (qid) for 7–10 days
• Preferred regimen (2): (Ciprofloxacin 500 mg by mouth (po) bid OR levofloxacin 500 mg intravenously (IV)/po every 24 hours × 60 days is recommended for bioterrorism cases because of presumed aerosol exposure

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• Bacillary Angiomatosis and Cat Scratch Disease

• Preferred regimen (1): (azithromycin

• Patients >45 kg: 500 mg on day 1 followed by 250 mg for 4 additional days
• Patients <45 kg: 10 mg/kg on day 1 and 5 mg/kg for 4 more days
• Preferred regimen (2): (erythromycin 500 mg by mouth (po) qid OR doxycycline 100 mg bid orally for 2 weeks to 2 months

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• Erysipeloid

• Preferred regimen: (Penicillin (500 mg qid) OR amoxicillin (500 mg 3 times daily [tid]) for 7–10 days

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• Glanders

• Preferred regimen: (Ceftazidime, gentamicin, imipenem, doxycycline, or ciprofloxacin is recommended based on in vitro susceptibility

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• Bubonic Plague

• Preferred regimen: (streptomycin (15 mg/kg intramuscularly [IM] every 12 hours) OR doxycycline (100 mg bid po) OR gentamicin could be substituted for streptomycin

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• Tularemia

• Preferred regimen (1): (streptomycin (15 mg/kg every 12 hours IM) OR gentamicin (1.5 mg/kg every 8 hours IV)
• Preferred regimen (2): (tetracycline (500 mg qid) OR doxycycline (100 mg bid po) is recommended for treatment of mild cases of tularemia

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• Mastitis

• Breast Implant
• Non-puerpural mastitis
• Postpartum mastitis

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• Abscess

• Boils
• Furuncles
• Furunculosis, recurrent
• Pilonidal cyst

• Paronychia
• Acne

• Rosacea
• Acne vulgaris

• Cutaneous anthrax
• Bacillary angiomatosis
• Bullous or vesicular lesions

• Bullous impetigo
• Chickenpox
• Hemorrhagic
• Herpes simplex
• Herpes zoster
• Shingles
• Staphylococcal scalded skin syndrome
• Varicella
• Vibro species

• Cellulitis

• Cellulitis in diabetic patients
• Erysipelas
• Facial cellulitis
• Cellulitis in non-diabetic patients
• Orbital cellulitis
• Cellulitis caused by Vibro species

• Burns

• Non-infected wound
• Infected wound

• Erythema nodosum
• Superficial infections

• Ecthyma
• Impetigo, crusted
• Impetigo, bullous
• Folliculitis
• Seborrheic dermatitis

• Lyme disease

• Lyme disease, Early
• Lyme disease, Post-exposure prophylaxis
• Lyme disease, Post-lyme disease syndrome

• Ecthyma contagiosum
• Erythrasma
• Vascular insufficieny ulcers
• Wound infections

• Post-operative, negative Gram-stain
• Post-operative, positive Gram-stain
• Post-trauma

• Yaws