Differentiating Metabolic syndrome from other diseases: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{ | [[Image:Home_logo1.png|right|250px|link=https://www.wikidoc.org/index.php/Metabolic_syndrome]] | ||
{{ | {{CMG}}; {{AE}} {{MMF}} | ||
==Overview== | ==Overview== | ||
Metabolic syndrome syndrome must be differentiated from other diseases that cause [[hypertension]], [[obesity]], and [[hyperandrogenism]], such as [[Cushing's syndrome]] and [[pseudo-Cushing's syndrome]]. | |||
==Differentiating Metabolic Syndrome from other Diseases== | ==Differentiating Metabolic Syndrome from other Diseases== | ||
The table below summarizes the findings that differentiate Cushing's disease from other conditions that may cause [[Hypertension| | The table below summarizes the findings that differentiate pseudo-Cushing's disease from other conditions that may cause [[Hypertension|hypertension]]<nowiki/>, [[hyperandrogenism]], [[obesity]], [[Facial|facial plethora]], skin changes, [[osteoporosis]], [[nephrolithiasis]] and [[neuropsychiatric]] conditions.<ref name="pmid11253984">{{cite journal |vauthors=Boscaro M, Barzon L, Fallo F, Sonino N |title=Cushing's syndrome |journal=Lancet |volume=357 |issue=9258 |pages=783–91 |year=2001 |pmid=11253984 |doi=10.1016/S0140-6736(00)04172-6 |url=}}</ref><ref name="pmid11571938">{{cite journal |vauthors=Findling JW, Raff H |title=Diagnosis and differential diagnosis of Cushing's syndrome |journal=Endocrinol. Metab. Clin. North Am. |volume=30 |issue=3 |pages=729–47 |year=2001 |pmid=11571938 |doi= |url=}}</ref><ref name="pmid9793762">{{cite journal |vauthors=Newell-Price J, Trainer P, Besser M, Grossman A |title=The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states |journal=Endocr. Rev. |volume=19 |issue=5 |pages=647–72 |year=1998 |pmid=9793762 |doi=10.1210/edrv.19.5.0346 |url=}}</ref><ref name="urlHow Is Metabolic Syndrome Diagnosed? - NHLBI, NIH">{{cite web |url=https://www.nhlbi.nih.gov/health/health-topics/topics/ms/diagnosis |title=How Is Metabolic Syndrome Diagnosed? - NHLBI, NIH |format= |work= |accessdate=}}</ref> | ||
<br> | <br> | ||
{| align="center" | {| align="center" | ||
|- | |- | ||
| | | | ||
{| style="border: 0px; font-size: 90%; margin: 3px; | {| align="center" style="border: 0px; font-size: 90%; margin: 3px;" | ||
! style="background:#4479BA; color: #FFFFFF;" | Conditions | ! style="background:#4479BA; color: #FFFFFF;" | Conditions | ||
! style="background:#4479BA; color: #FFFFFF;" |Causes | ! style="background:#4479BA; color: #FFFFFF;" |Causes | ||
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|- | |- | ||
| align="center" style="background:#DCDCDC;" |[[Metabolic syndrome X]] | | align="center" style="background:#DCDCDC;" |[[Metabolic syndrome X]] | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
*Familial/genetic | *[[Genetics|Familial/genetic]] | ||
*Obesity | *[[Obesity]] | ||
*Insulin resistance | *[[Insulin]] resistance | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
* [[Obesity]] | * [[Obesity]] | ||
*[[Hypertension]] | *[[Hypertension]] | ||
| Line 29: | Line 29: | ||
*[[Dyslipidemia]] | *[[Dyslipidemia]] | ||
*[[Diabetes mellitus|Diabetes]]/[[Glucose intolerance]] | *[[Diabetes mellitus|Diabetes]]/[[Glucose intolerance]] | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
*Waist circumference | *Waist circumference | ||
*[[Lipoproteins|Low-density lipoproteins]] | *[[Lipoproteins|Low-density lipoproteins]] | ||
| Line 38: | Line 38: | ||
|- | |- | ||
| align="center" style="background:#DCDCDC;" |[[Cushing's syndrome]] | | align="center" style="background:#DCDCDC;" |[[Cushing's syndrome]] | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
*Iatrogenic | *Iatrogenic | ||
*Pituitary adenoma | *[[Pituitary adenoma]] | ||
*Adrenal tumor | *[[Adrenal tumor]] | ||
*Adrenal hyperplasia | *[[Adrenal hyperplasia]] | ||
*Ectopic ACTH secretion | *Ectopic [[ACTH]] secretion | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
* [[Obesity]] | * [[Obesity]] | ||
*[[Hypertension]] | *[[Hypertension]] | ||
| Line 53: | Line 53: | ||
*Neuropsychiatric problems | *Neuropsychiatric problems | ||
*[[Kidney stone|Kidney stones]] | *[[Kidney stone|Kidney stones]] | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
*24-hour urine cortisol | *24-hour urine [[cortisol]] | ||
*Midnight salivary cortisol | *Midnight salivary [[cortisol]] | ||
*Low dose dexamethasone challenge test | *Low dose [[dexamethasone]] challenge test | ||
*CRH stimulation | *[[CRH]] stimulation | ||
*High dose dexamethasone test | *High dose [[dexamethasone]] test | ||
*MRI brain | *[[MRI]] brain | ||
*CT/MRI adrenals | *[[CT]]/[[MRI]] [[Adrenal|adrenals]] | ||
|- | |- | ||
| align="center" style="background:#DCDCDC;" |[[Pseudo-Cushing's syndrome]] | | align="center" style="background:#DCDCDC;" |[[Pseudo-Cushing's syndrome]] | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
*Obesity | *[[Obesity]] | ||
*Alcoholism | *[[Alcoholism]] | ||
*Depression | *[[Depression]] | ||
*HIV | *[[HIV]] | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
* [[Obesity]] | * [[Obesity]] | ||
*[[Hypertension]] | *[[Hypertension]] | ||
*[[PCOS]]/[[hyperandrogenism]] | *[[PCOS]]/[[hyperandrogenism]] | ||
*[[Oligomenorrhea]]/[[hypogonadism]] | *[[Oligomenorrhea]]/[[hypogonadism]] | ||
| style="padding: 5px 5px; background: #F5F5F5; | | align="left" style="padding: 5px 5px; background: #F5F5F5;" | | ||
*Urinary free cortisol | *Urinary free [[cortisol]] | ||
*Midnight salivary cortisol | *Midnight salivary [[cortisol]] | ||
*Low dose dexamethasone challenge test | *Low dose [[dexamethasone]] challenge test | ||
*[[Glucose tolerance test]] | *[[Glucose tolerance test]] | ||
*Loperamide test | *[[Loperamide]] test | ||
|} | |} | ||
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[[Category:Needs content]] | [[Category:Needs content]] | ||
[[Category:Needs overview]] | [[Category:Needs overview]] | ||
|} | |||
Latest revision as of 22:38, 25 February 2019
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Furqan M M. M.B.B.S[2]
Overview
Metabolic syndrome syndrome must be differentiated from other diseases that cause hypertension, obesity, and hyperandrogenism, such as Cushing's syndrome and pseudo-Cushing's syndrome.
Differentiating Metabolic Syndrome from other Diseases
The table below summarizes the findings that differentiate pseudo-Cushing's disease from other conditions that may cause hypertension, hyperandrogenism, obesity, facial plethora, skin changes, osteoporosis, nephrolithiasis and neuropsychiatric conditions.[1][2][3][4]
References
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