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{{Gastric dumping syndrome}}
{{Gastric dumping syndrome}}
{{CMG}}
{{CMG}}; {{AE}} {{UA}}


==Overview==
==Overview==
[[Gastric dumping syndrome|Dumping syndrome]] can be divided into early dumping and late dumping syndrome based upon the timeline of onset of [[symptoms]] and clinical features.


==Classification==
==Classification==
* '''Early dumping''' begins during or right after a meal.
Dumping syndrome may be classified based upon the timeline of the onset of [[symptoms]] and clinical features. The following table depicts the major classification systems of dumping syndrome :<ref name="pmid1549803">{{cite journal |vauthors=Eagon JC, Miedema BW, Kelly KA |title=Postgastrectomy syndromes |journal=Surg. Clin. North Am. |volume=72 |issue=2 |pages=445–65 |year=1992 |pmid=1549803 |doi= |url=}}</ref><ref name="pmid1990879">{{cite journal |vauthors=Miedema BW, Kelly KA |title=The Roux operation for postgastrectomy syndromes |journal=Am. J. Surg. |volume=161 |issue=2 |pages=256–61 |year=1991 |pmid=1990879 |doi= |url=}}</ref><ref name="pmid9279532">{{cite journal |vauthors=Vecht J, Gielkens HA, Frölich M, Lamers CB, Masclee AA |title=Vasoactive substances in early dumping syndrome: effects of dumping provocation with and without octreotide |journal=Eur. J. Clin. Invest. |volume=27 |issue=8 |pages=680–4 |year=1997 |pmid=9279532 |doi= |url=}}</ref>
 
{| class="wikitable" style="margin: 1em auto 1em auto"
* '''Late dumping''' happens 1 to 3 hours after eating.
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Clinical Features
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Early Dumping
! align="center" style="background:#4479BA; color: #FFFFFF;" + |Late Dumping
|-
|'''Onset'''
|15-30 minutes after a meal
|60-180 minutes after a meal
|-
|'''Risk Factor'''
|[[Bariatrics|Bariatric]] [[Surgery]]
|[[Hyperosmolar]] [[chyme]]
|-
|'''Mechanism'''
|
* Increased release of multiple [[Gastrointestinal tract|gastrointestinal]] [[Hormone|hormones]]
* Decrease in [[Stomach|gastric]] [[volume]]
* Impaired [[retention]]
* Possible [[Pylorus|pyloric]] dysfunction
|
* Rapid [[glucose]] absorption
* [[Incretin]] release ([[Glucagon-like peptide-1|GLP-1]])
* Amplified [[insulin]] [[secretion]]
|-
|'''Symptoms'''
|
* [[Nausea and vomiting|Nausea]]
* [[Bloating]]
* [[Nausea and vomiting|Vomiting]]
* [[Diarrhea]]
* [[Borborygmus]]
* [[Epigastric]] fullness
* [[Abdominal]] [[Cramp|cramps]]
* [[Diaphoresis]]
* Desire to lie down
* [[Headache]]
* [[Flushing]]
* [[Fatigue]]
* [[Dizziness|Lightheadedness]]
* [[Pallor]]
* [[Palpitation|Palpitations]]
* [[Syncope]]
|
* [[Tremor]]
* [[Hunger]]
* [[Perspiration]]
* Difficulty with [[concentration]]
* Decreased [[consciousness]]
|-
|'''Hormones'''
|
* [[Vasoactive]] agents ([[Vasoactive intestinal peptide|VIP]], [[Neurotensin]])
* [[Incretin|Incretins]] ([[Gastric inhibitory polypeptide]]- [[Gastric inhibitory polypeptide|GIP]], [[Glucagon-like peptide-1|glucagon like peptide]]- [[Glucagon-like peptide-1|GLP-1)]]
* [[Glucose]]-modulating [[Hormone|hormones]] ([[Glucagon]], [[Insulin]])
|
* [[Incretin]]
|-
|'''Common Complication'''
|[[Vasomotor]] [[Symptom|symptoms]]
|[[Hypoglycemia]] (high [[Insulin]])
|}


==References==
==References==

Latest revision as of 18:15, 13 December 2017

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Umar Ahmad, M.D.[2]

Overview

Dumping syndrome can be divided into early dumping and late dumping syndrome based upon the timeline of onset of symptoms and clinical features.

Classification

Dumping syndrome may be classified based upon the timeline of the onset of symptoms and clinical features. The following table depicts the major classification systems of dumping syndrome :[1][2][3]

Clinical Features Early Dumping Late Dumping
Onset 15-30 minutes after a meal 60-180 minutes after a meal
Risk Factor Bariatric Surgery Hyperosmolar chyme
Mechanism
Symptoms
Hormones
Common Complication Vasomotor symptoms Hypoglycemia (high Insulin)

References

  1. Eagon JC, Miedema BW, Kelly KA (1992). "Postgastrectomy syndromes". Surg. Clin. North Am. 72 (2): 445–65. PMID 1549803.
  2. Miedema BW, Kelly KA (1991). "The Roux operation for postgastrectomy syndromes". Am. J. Surg. 161 (2): 256–61. PMID 1990879.
  3. Vecht J, Gielkens HA, Frölich M, Lamers CB, Masclee AA (1997). "Vasoactive substances in early dumping syndrome: effects of dumping provocation with and without octreotide". Eur. J. Clin. Invest. 27 (8): 680–4. PMID 9279532.

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