Gastric dumping syndrome future or investigational therapies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Umar Ahmad, M.D.[2]
Overview
Investigational therapies of dumping syndrome include continuous enteral feeding, drugs, electrical pacing of the stomach and surgical re-intervention.
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Future or Investigational Therapies
Procedures
- Continuous enteral feeding.[1]
- Electrical stimulation of the small intestine to achieve gastrointestinal pacing in dumping syndrome.[2]
- In dogs prepared with truncal vagotomy, distal gastrectomy, and Roux-en-Y reconstruction, retrograde electrical pacing of the Roux-en-Y reconstruction significantly delayed gastric emptying and absorption of a glucose meal and decreased postcibal hemoconcentration.
Drugs
Verapamil may be considered.[3]
References
- ↑ Tack J, Arts J, Caenepeel P, De Wulf D, Bisschops R (2009). "Pathophysiology, diagnosis and management of postoperative dumping syndrome". Nat Rev Gastroenterol Hepatol. 6 (10): 583–90. doi:10.1038/nrgastro.2009.148. PMID 19724252.
- ↑ Zhang J, Chen JD (2006). "Pacing the gut in motility disorders". Curr Treat Options Gastroenterol. 9 (4): 351–60. PMID 16836954.
- ↑ Chandos B (1992). "Dumping syndrome and the regulation of peptide YY with verapamil". Am. J. Gastroenterol. 87 (10): 1530–1. PMID 1415124.