Uridine monophosphate

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Template:Chembox new Uridine monophosphate, also known as 5'-uridylic acid and abbreviated UMP, is a nucleotide that is found in RNA. It is an ester of phosphoric acid with the nucleoside uridine. UMP consists of the phosphate group, the pentose sugar ribose, and the nucleobase uracil. Another common shorthand for the molecule is uridylate - the deprotonated form of the molecule, which is predominant in aqueous solution.

Biosynthesis

Uridine monophosphate is formed from orotidylic acid in a decarboxylation reaction catalyzed by the enzyme orotidylate decarboxylase. Uncatalyzed, the decarboxylation reaction is extremely slow (estimated to occur on average one time per 78 million years). Adequately catalyzed, the reaction takes place once per second, an increase of 1017-fold. [1]

References

  1. Berg J, Tymoczko JL, Stryer L (2006). Biochemistry (6th ed. ed.). San Francisco: W. H. Freeman. ISBN 0716787245.<templatestyles src="Module:Citation/CS1/styles.css"></templatestyles>

See also

Template:Nucleic acids

da:UMP (kemi) it:Uridinmonofosfato

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