Thin basement membrane disease medical therapy

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Thin basement membrane disease Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Marufa Marium, M.B.B.S[2]

Overview

There is no treatment for Thin basement membrane disease; the mainstay of therapy is supportive care.

Medical Therapy

There are no treatment regimen available for TBMD on the basis of evidence. It is a benign condition. After diagnosing it with renal biopsy, patient and affected family members are monitored for new onset hypertension, proteinuria and renal function yearly or once every two years. Regular monitoring is must for the patient who has proteinuria >500mg/dL or renal insufficiency and hypertension. They should be treated according to their symptoms. ACEI or ARB are used to treat persistent proteinuria.[1]

References

  1. Savige J, Rana K, Tonna S, Buzza M, Dagher H, Wang YY (October 2003). "Thin basement membrane nephropathy". Kidney Int. 64 (4): 1169–78. doi:10.1046/j.1523-1755.2003.00234.x. PMID 12969134.

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