Struma ovarii history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aravind Reddy Kothagadi M.B.B.S[2]


The most common presenting symptoms are pelvic painabdominal distension followed by abnormal vaginal bleeding. Other symptoms such as anorexia, dyschezianauseafeverintestinal obstruction, frequent micturition and ascites may also be seen.

History and Symptoms


Patients with struma ovarii may have a positive history of: [1][2]

Common Symptoms

Common symptoms of struma ovarii include:[2][3]

Less Common Symptoms

Less common symptoms of struma ovarii include: [2][3]


  1. Kempers RD, Dockerty MB, Hoffman DL, Bartholomew LG (1970). "Struma ovarii--ascitic, hyperthyroid, and asymptomatic syndromes". Ann. Intern. Med. 72 (6): 883–93. PMID 5448747.
  2. 2.0 2.1 2.2 Yoo SC, Chang KH, Lyu MO, Chang SJ, Ryu HS, Kim HS (2008). "Clinical characteristics of struma ovarii". J Gynecol Oncol. 19 (2): 135–8. doi:10.3802/jgo.2008.19.2.135. PMC 2676458. PMID 19471561.
  3. 3.0 3.1 Tanimanidis P, Chatzistamatiou K, Nikolaidou A, Kaplanis K (2014). "Struma ovarii. A case report". Hippokratia. 18 (4): 357–8. PMC 4453812. PMID 26052205.
  4. 4.0 4.1 4.2 4.3 4.4 4.5 Luo JR, Xie CB, Li ZH (2014). "Treatment for malignant struma ovarii in the eyes of thyroid surgeons: a case report and study of Chinese cases reported in the literature". Medicine (Baltimore). 93 (26): e147. doi:10.1097/MD.0000000000000147. PMC 4616397. PMID 25474425.
  5. Bokhari A, Rosenfeld GS, Cracchiolo B, Heller DS (2003). "Cystic struma ovarii presenting with ascites and an elevated CA-125 level. A case report". J Reprod Med. 48 (1): 52–6. PMID 12611097.
  6. Rim SY, Kim SM, Choi HS (2005). "Struma ovarii showing clinical characteristics of ovarian malignancy". Int. J. Gynecol. Cancer. 15 (6): 1156–9. doi:10.1111/j.1525-1438.2005.00328.x. PMID 16343201.
  7. Nagai, Koichi; Yoshida, Hiroshi; Katayama, Kayo; Ishidera, Yumi; Oi, Yuka; Ando, Noriko; Shigeta, Hiroyuki (2017). "Hyperthyroidism due to struma ovarii: Diagnostic pitfalls and preventing thyroid storm". Gynecology and Minimally Invasive Therapy. 6 (1): 28–30. doi:10.1016/j.gmit.2016.05.002. ISSN 2213-3070.
  8. Dujardin MI, Sekhri P, Turnbull LW (2014). "Struma ovarii: role of imaging?". Insights Imaging. 5 (1): 41–51. doi:10.1007/s13244-013-0303-3. PMC 3948908. PMID 24357453.
  9. Outwater EK, Siegelman ES, Hunt JL (2001). "Ovarian teratomas: tumor types and imaging characteristics". Radiographics. 21 (2): 475–90. doi:10.1148/radiographics.21.2.g01mr09475. PMID 11259710.

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