Scleroderma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]


High-resolution CT (HRCT) scan of the chest may be helpful in the diagnosis of scleroderma interstitial lung disease and pulmonary hypertension. Findings on HRCT suggestive of interstitial lung disease include architectural distortion due to pulmonary fibrosis, reticular interlobular interstitial thickening, increased ground glass opacity and accentuated reticular markings on juxtapleural, posterior and basilar portion of the lungs, traction bronchiectasis and honeycomb cystic change.

CT scan

High-resolution CT (HRCT) scan of the chest may be helpful in the diagnosis of scleroderma interstitial lung disease and pulmonary hypertension. Findings on CT scan suggestive of interstitial lung disease include:[1][2][3][4]


  1. Swensen SJ, Aughenbaugh GL, Myers JL (October 1997). "Diffuse lung disease: diagnostic accuracy of CT in patients undergoing surgical biopsy of the lung". Radiology. 205 (1): 229–34. doi:10.1148/radiology.205.1.9314990. PMID 9314990.
  2. Müller NL, Coiby TV (1997). "Idiopathic interstitial pneumonias: high-resolution CT and histologic findings". Radiographics. 17 (4): 1016–22. doi:10.1148/radiographics.17.4.9225401. PMID 9225401.
  3. Goldin JG, Lynch DA, Strollo DC, Suh RD, Schraufnagel DE, Clements PJ, Elashoff RM, Furst DE, Vasunilashorn S, McNitt-Gray MF, Brown MS, Roth MD, Tashkin DP (August 2008). "High-resolution CT scan findings in patients with symptomatic scleroderma-related interstitial lung disease". Chest. 134 (2): 358–367. doi:10.1378/chest.07-2444. PMID 18641099.
  4. Schurawitzki H, Stiglbauer R, Graninger W, Herold C, Pölzleitner D, Burghuber OC, Tscholakoff D (September 1990). "Interstitial lung disease in progressive systemic sclerosis: high-resolution CT versus radiography". Radiology. 176 (3): 755–9. doi:10.1148/radiology.176.3.2389033. PMID 2389033.

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