Retinoblastoma history and symptoms
Retinoblastoma history and symptoms On the Web
American Roentgen Ray Society Images of Retinoblastoma history and symptoms
The hallmark of retinoblastoma is leukocoria, which is an abnormal appearance of the retina as viewed through the pupil, also known as amaurotic cat's eye reflex. Common symptoms of retinoblastoma include strabismus and proptosis. The clinical presentation depends on the stage of the disease.
History and Symptoms
- History of a patient with retinoblastoma may include the:
- Clinical features of retinoblatoma are approximately the same in variable studies and the common findings are as follow:
- Presenting symptoms in adult onset of the tumor are insidious and can include:
- Advanced and/or metastatic form of the tumor also presents with constitutional symptoms, such as:
- Patients with retinoblastoma may also present with delay in developmental milestones and intellectual disability which may be perceived by their caregivers.
- Shields CL, Shields JA, Baez K, Cater JR, De Potter P (February 1994). "Optic nerve invasion of retinoblastoma. Metastatic potential and clinical risk factors". Cancer. 73 (3): 692–8. PMID 8299091.
- Chebbi A, Bouguila H, Boussaid S, Ben Aleya N, Zgholi H, Malek I, Zeghal I, Nacef L (June 2014). "[Clinical features of retinoblastoma in Tunisia]". J Fr Ophtalmol (in French). 37 (6): 442–8. doi:10.1016/j.jfo.2014.01.009. PMID 24792399.
- Abramson DH, Beaverson K, Sangani P, Vora RA, Lee TC, Hochberg HM, Kirszrot J, Ranjithan M (December 2003). "Screening for retinoblastoma: presenting signs as prognosticators of patient and ocular survival". Pediatrics. 112 (6 Pt 1): 1248–55. PMID 14654593.
- Shifa, Jemal Zeberga; Gezmu, Alemayehu Mekonnen (2017). "Presenting signs of retinoblastoma at a tertiary level teaching hospital in Ethiopia". Pan African Medical Journal. 28. doi:10.11604/pamj.2017.28.66.11199. ISSN 1937-8688.
- Khetan, Vikas; Sengupta, Sabyasachi; Pan, Utsab (2016). "Adult onset retinoblastoma". Indian Journal of Ophthalmology. 64 (7): 485. doi:10.4103/0301-4738.190099. ISSN 0301-4738.
- Image courtesy of Dr. Frank Gaillard Radiopaedia (original file ).[http://radiopaedia.org/licence Creative Commons BY-SA-NC
- Clark, Robin D.; Avishay, Stefanie G. (2015). "Retinoblastoma: Genetic Counseling and Testing": 77–88. doi:10.1007/978-3-662-43451-2_8.