Post-thrombotic syndrome risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Risk Factors
Investigators have determined that the following factors increase patients’ risk of developing PTS:[1][2][3][4][5][6][7]
- age > 65
- proximal DVT
- a second DVT in same leg as first DVT (recurrent ipsilateral DVT)
- persistent DVT symptoms 1 month after DVT diagnosis
- obesity
- poor quality of anticoagulation control (i.e. dose too low) during the first 3 months of treatment
References
- ↑ Tick LW, Kramer MH, Rosendaal FR, Faber WR, Doggen CJ. Risk factors for post-thrombotic syndrome in patients with a first deep venous thrombosis. J Thromb Haemost. 2008;6:2075-81.
- ↑ Prandoni P, Lensing AWA, Cogo A, Cuppini S, Villalta S, Carta M, et al. The long-term clinical course of acute deep venous thrombosis. Ann Intern Med 1996;125:1-7.
- ↑ Shbaklo H, Kahn SR. Long-term prognosis after deep venous thrombosis. Curr Opin Hematol 2008;15:494-8.
- ↑ Kahn SR, Kearon C, Julian JA, Mackinnon B, Kovacs MJ, Wells P, et al. Predictors of the post-thrombotic syndrome during long-term treatment of proximal deep vein thrombosis. J Thromb Haemost 2005;3:718-23.
- ↑ Ageno W, Piantanida E, Dentali F, Steidl L, Mera V, Squizzato A, et al. Body mass index is associated with the development of the post-thrombotic syndrome. Thromb Haemost 2003;89:305-9.
- ↑ van Dongen CJ, Prandoni P, Frulla M, Marchiori A, Prins MH, Hutten BA. Relation between quality of anticoagulant treatment and the development of the postthrombotic syndrome. J Thromb Haemost 2005;3:939-42.
- ↑ Kahn SR, Ginsberg JS. Relationship between deep venous thrombosis and the postthrombotic syndrome. Arch Intern Med 2004;164:17-26.