Palmar plantar erythrodysesthesia physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mandana Chitsazan, M.D. [2]

Overview

Physical examination of patients with PPE depends on the grade of the disease. Determination of toxicity grading of PPE requires both visual assessment and patient description of symptoms. Skin findings include erythema, edema, hyperkeratosis, peeling, blisters, bleeding, and fissures.

Physical Examination

Physical examination of patients with PPE depends on the grade of the disease. Determination of toxicity grading of PPE requires both visual assessment and patient description of symptoms.

Appearance of the Patient

  • Patients with PPE usually appear normal.

Vital Signs

Skin

HEENT

Neck

Lungs

Heart

Abdomen

Back

Genitourinary

Neuromuscular

Extremities

  • Extremities examination, excluding the neuromuscular and skin findings, in patients with PPE is usually normal.

References

  1. "Protocol Development | CTEP".
  2. Hui YF, Cortes JE (2000). "Palmar-plantar erythrodysesthesia syndrome associated with liposomal daunorubicin". Pharmacotherapy. 20 (10): 1221–3. PMID 11034047.
  3. "www.oncologynurseadvisor.com".