Ogilvie syndrome medical therapy

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Ogilvie syndrome Microchapters


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]


Supportive care is the first line of management of the colonic pseudo-obstruction. The supportive measures include treatment of the underlying cause of the obstruction, terminating the concurrent medications that may cause intestinal dysmotility, and administration of intravenous fluids and salineNeostigmine can be used in the cases of pseudo-obstruction resistant to the supportive measures. Non-surgical techniques can be performed to decompress the obstructionand it includes colonoscopic decompression and percutaneous cecostomy.

Medical Therapy

Supportive care

Medical therapy


Decompression techniques


  1. Eisen GM, Baron TH, Dominitz JA, Faigel DO, Goldstein JL, Johanson JF; et al. (2002). "Acute colonic pseudo-obstruction". Gastrointest Endosc. 56 (6): 789–92. PMID 12447286.
  2. Sloyer AF, Panella VS, Demas BE, Shike M, Lightdale CJ, Winawer SJ; et al. (1988). "Ogilvie's syndrome. Successful management without colonoscopy". Dig Dis Sci. 33 (11): 1391–6. PMID 3180976.
  3. Rausch ME, Troiano NH, Rosen T (2007). "Use of neostigmine to relieve a suspected colonic pseudoobstruction in pregnancy". J Perinatol. 27 (4): 244–6. doi:10.1038/sj.jp.7211669. PMID 17377607.
  4. Saunders MD, Kimmey MB (2005). "Systematic review: acute colonic pseudo-obstruction". Aliment Pharmacol Ther. 22 (10): 917–25. doi:10.1111/j.1365-2036.2005.02668.x. PMID 16268965.
  5. Jetmore AB, Timmcke AE, Gathright JB, Hicks TC, Ray JE, Baker JW (1992). "Ogilvie's syndrome: colonoscopic decompression and analysis of predisposing factors". Dis Colon Rectum. 35 (12): 1135–42. PMID 1473414.
  6. Geller A, Petersen BT, Gostout CJ (1996). "Endoscopic decompression for acute colonic pseudo-obstruction". Gastrointest Endosc. 44 (2): 144–50. PMID 8858319.
  7. vanSonnenberg E, Varney RR, Casola G, Macaulay S, Wittich GR, Polansky AM; et al. (1990). "Percutaneous cecostomy for Ogilvie syndrome: laboratory observations and clinical experience". Radiology. 175 (3): 679–82. doi:10.1148/radiology.175.3.2343112. PMID 2343112.