Myelodysplastic syndrome medical therapy
Jump to navigation Jump to search
Myelodysplastic syndrome Microchapters
Differentiating Myelodysplastic syndrome from other Diseases
Myelodysplastic syndrome medical therapy On the Web
American Roentgen Ray Society Images of Myelodysplastic syndrome medical therapy
Risk calculators and risk factors for Myelodysplastic syndrome medical therapy
Editor-In-Chief: C. Michael Gibson, M.S., M.D. ;Associate Editor(s)-in-Chief: Nawal Muazam M.D.
Chemotherapy is recommended among all patients who develop myelodysplastic syndrome.
- Treatment is based on the type of myelodysplastic syndrome and the person's age and general health. The goal of treatment for myelodysplastic syndrome is to:
- Relieve symptoms
- Slow or prevent progression of the disease
- Improve quality of life
- The most common chemotherapy drug used to treat myelodysplastic syndrome is cytarabine. Cytarabine may be combined with other pharmacological agents such as:
- Other chemotherapeutic agents that may be used to treat myelodysplastic syndrome include:
- Supportive therapy is given to relieve symptoms and lessen the problems caused by abnormal blood cell counts or treatment for myelodysplastic syndrome.
- Patients with anemia may receive blood transfusions to correct the red blood cell counts.
- Frequent blood transfusions can be complicated by a buildup of extra iron in the body, which is treated with drug therapy.
- Patients with bleeding problems due to low platelet counts may be given platelet transfusions.
- Epoetin (erythropoietin)
- Helps improve production of red blood cells
- Also called granulocyte colony-stimulating factor (G-CSF)
- Helps improve production of white blood cells
- A long-acting G-CSF
- Other drugs that may be used to treat symptoms or side effects of therapy include:
- treats excess iron in the blood
- sometimes given with Vitamin C.
- decreases the need for transfusions in people with a specific chromosome change
- decreases the need for transfusions in certain types of myelodysplastic syndrome
- help to prevent or treat infections
- Hypomethylating agents, such as 5-azacytidine or decitabine
- stop cancer cells from producing DNA or RNA so the cells die