Multiple myeloma MRI

Jump to navigation Jump to search

Multiple myeloma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Multiple Myeloma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Criteria

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

Echocardiograph and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Future or Investigational Therapies

Case Studies

Case #1

Multiple myeloma MRI On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Multiple myeloma MRI

All Images
X-rays
Echo and Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Multiple myeloma MRI

CDC on Multiple myeloma MRI

Multiple myeloma MRI in the news

Blogs on Multiple myeloma MRI

Directions to Hospitals Treating Multiple myeloma

Risk calculators and risk factors for Multiple myeloma MRI

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Hannan Javed, M.D.[2]; Haytham Allaham, M.D. [3]; Shyam Patel [4]

Overview

MRI may be diagnostic of multiple myeloma.[1]Findings on MRI suggestive of multiple myeloma include infiltration and replacement of the bone marrow.[2][3] MRI is a more expensive test than an X-ray.

MRI

Magnetic resonance imaging (MRI) is more sensitive than simple X-ray in the detection of lytic lesions of multiple myeloma.[2] The International Myeloma Working Group (IMWG) recently proposed revised imaging criteria for a diagnosis of multiple myeloma. The MRI criteria is the presence of greater than 1 focal lesion of at least 5mm in size. Of note, MRI is the most expensive of the imaging tests. X-rays may sometimes be a sufficient substitute for assessing for the presence of lytic lesions for patients who are symptomatic. However, X-rays carry a risk for radiation exposure, unlike MRI. Clinical judgment should be used when determining whether to order MRI or X-rays to assess for lytic lesions. MRI may supersede skeletal survey, especially when vertebral disease is suspected.[2]

  • Shown below is a series of MRI images in a multiple myeloma patient complaining of back pain.

References

  1. Gerecke C, Fuhrmann S, Strifler S, Schmidt-Hieber M, Einsele H, Knop S (July 2016). "The Diagnosis and Treatment of Multiple Myeloma". Dtsch Arztebl Int. 113 (27–28): 470–6. doi:10.3238/arztebl.2016.0470. PMC 4973001. PMID 27476706.
  2. 2.0 2.1 2.2 Multiple myeloma. Radiopaedia(2015) http://radiopaedia.org/articles/multiple-myeloma-1 Accessed on September, 20th 2015
  3. Reisenbuckler C (2014). "Multiple myeloma and diagnostic imaging". Radiol Technol. 85 (4): 391–410, quiz 411–3. PMID 24614435.