Mitral valve prolapse (patient information)

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Mitral valve prolapse
ICD-10 I34.1
ICD-9 394.0, 424.0
OMIM 157700
DiseasesDB 8303
MedlinePlus 000180
MeSH D008945

Mitral valve prolapse


What are the symptoms?

What are the causes?

Who is at highest risk?


When to seek urgent medical care?

Treatment options

Where to find medical care for Mitral valve prolapse?


What to expect (Outlook/Prognosis)?

Possible complications

Mitral valve prolapse On the Web

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Videos on Mitral valve prolapse

FDA on Mitral valve prolapse

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Directions to Hospitals Treating Mitral valve prolapse

Risk calculators and risk factors for Mitral valve prolapse

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Editor-in-Chief: C. Michael Gibson, M.S.,M.D. [1] Phone:617-632-7753; Editor(s)-In-Chief Patient Information Page: Meagan E. Doherty; Lakshmi Gopalakrishnan, M.B.B.S.

Keywords or synonyms: MVP, floppy mitral valve


Mitral valve prolapse (MVP) occurs when one of your heart's valves doesn't work properly. MVP is one of the more common heart valve conditions. Most often, it's a lifelong condition that a person is born with. Most people with MVP have no symptoms or problems, need no treatment, and are able to lead normal, active lives.

What are the symptoms of Mitral valve prolapse?

  • Many patients with mitral valve prolapse do not have symptoms.
  • The group of symptoms found in patients with mitral valve prolapse is called mitral valve prolapse syndrome and includes:

Note: There may be no symptoms, or symptoms may develop slowly

What causes Mitral valve prolapse?

  • The mitral valve helps blood on the left side of the heart flow in one direction. It closes to keep blood from moving backwards when the heart beats (contracts).
  • Mitral valve prolapse is the term used when the valve does not close properly. It can be caused by many different things. In most cases, it is harmless and patients usually do not know they have the problem. As much as 10% of the population has some minor, insignificant form of mitral valve prolapse, but it does not generally affect their lifestyle.
  • In a small number of cases, the prolapse can cause blood to leak backwards. This is called mitral regurgitation.
  • Mitral valves that are structurally abnormal can raise the risk for bacterial infection.
  • Some forms of mitral valve prolapse seem to be passed down through families (inherited). Mitral valve prolapse has been associated with Graves disease.
  • Mitral valve prolapse often affects thin women who may have minor chest wall deformities, scoliosis, or other disorders.
  • Mitral valve prolapse is associated with some connective tissue disorders, especially Marfan syndrome. Other conditions include:


  • The doctor will perform a physical exam and use a stethoscope to listen to your heart and lungs. The doctor may feel a thrill (vibration) over the heart, and hear a heart murmur (midsystolic click). The murmur gets louder when you stand up.
  • The following tests may be used to diagnose mitral valve prolapse or a leaky mitral valve:

When to Seek Urgent Medical Care

Call your health care provider if you have:

  • Chest discomfort, palpitations, or fainting spells that get worse
  • Long-term illnesses with fevers

Treatment Options

  • Most of the time, there are no (or few) symptoms, and treatment is not needed.
  • If you have severe mitral valve prolapse, you may need to stay in the hospital. You may need surgery to repair or replace the valve if you have severe mitral regurgitation or your symptoms get worse.
  • Mitral valve replacement may be needed if:
  • You have symptoms
  • The left ventricle of the heart is enlarged
  • Heart function gets worse (depressed ejection fraction)
  • In the past, some people with mitral valve prolapse were given antibiotics before certain dental or surgical procedures to help prevent an infection called bacterial endocarditis (BE). However, the American Heart Association no longer recommends routine antibiotics before dental procedures or other surgical procedures for patients with only mitral valve prolapse, unless they have had bacterial endocarditis in the past.
  • Other drugs that may be prescribed when mitral regurgitation or other heart problems are also present:

Where to find Medical Care for Mitral valve prolapse

Directions to Hospitals Treating Mitral valve prolapse


You can't usually prevent mitral valve prolapse, but you can prevent certain complications. Tell your health care providers, including your dentist, if you have a history of heart disease or heart valve problems.

What to expect (Outlook/Prognosis)

Mitral valve prolapse should not negatively affect your lifestyle. If the leaky valve becomes severe, your outlook may be similar to that of people who have mitral regurgitation from any other cause.

Most of the time, the condition is harmless and does not cause symptoms. Symptoms that do occur can be treated and controlled with medicine or surgery. However, some irregular heartbeats (arrhythmias) associated with mitral valve prolapse can be life-threatening.

Possible complications


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