Hypopharyngeal cancer history and symptoms

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Hypopharyngeal cancer Microchapters


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Gertrude Djouka, M.D.[2], Faizan Sheraz, M.D. [3]


The hallmark of hypopharyngeal cancer is dysphagia. A positive history of tobacco use and abuse of alcohol consumption along with common symptoms of lump in the neck, odynophagia, dysphagia, and hoarseness are suggestive of hypopharyngeal cancer.

History and symptoms


Specific history should be focussed on:


Common symptoms of hypopharyngeal cancer include:[7][8][9][10][11]

Lung metastasis may occur in hypopharyngeal cancer and present symptoms.

For more information on symptoms of lung cancer, click here


  1. 1.0 1.1 Maasland, Denise HE; van den Brandt, Piet A; Kremer, Bernd; Goldbohm, R Alexandra; Schouten, Leo J (2014). "Alcohol consumption, cigarette smoking and the risk of subtypes of head-neck cancer: results from the Netherlands Cohort Study". BMC Cancer. 14 (1). doi:10.1186/1471-2407-14-187. ISSN 1471-2407.
  2. Novacek, Gottfried (2006). Orphanet Journal of Rare Diseases. 1 (1): 36. doi:10.1186/1750-1172-1-36. ISSN 1750-1172. Missing or empty |title= (help)
  3. Toland, Amanda Ewart; Joo, Young-Hoon; Lee, Youn-Soo; Cho, Kwang-Jae; Park, Jun-Ook; Nam, In-Chul; Kim, Chung-Soo; Kim, Sang-Yeon; Kim, Min-Sik (2013). "Characteristics and Prognostic Implications of High-Risk HPV-Associated Hypopharyngeal Cancers". PLoS ONE. 8 (11): e78718. doi:10.1371/journal.pone.0078718. ISSN 1932-6203.
  4. Guha, Neela; Warnakulasuriya, Saman; Vlaanderen, Jelle; Straif, Kurt (2014). "Betel quid chewing and the risk of oral and oropharyngeal cancers: A meta-analysis with implications for cancer control". International Journal of Cancer. 135 (6): 1433–1443. doi:10.1002/ijc.28643. ISSN 0020-7136.
  5. Auluck A, Hislop G, Poh C, Zhang L, Rosin MP (2009). "Areca nut and betel quid chewing among South Asian immigrants to Western countries and its implications for oral cancer screening". Rural Remote Health. 9 (2): 1118. PMC 2726113. PMID 19445556.
  6. Langevin SM, O'Sullivan MH, Valerio JL, Pawlita M, Applebaum KM, Eliot M, McClean MD, Kelsey KT (December 2013). "Occupational asbestos exposure is associated with pharyngeal squamous cell carcinoma in men from the greater Boston area". Occup Environ Med. 70 (12): 858–63. doi:10.1136/oemed-2013-101528. PMC 4227396. PMID 24142981.
  7. Pracy, P; Loughran, S; Good, J; Parmar, S; Goranova, R (2016). "Hypopharyngeal cancer: United Kingdom National Multidisciplinary Guidelines". The Journal of Laryngology & Otology. 130 (S2): S104–S110. doi:10.1017/S0022215116000529. ISSN 0022-2151.
  8. Barnes, Leon (2001). Surgical pathology of the head and neck. New York: M. Dekker. ISBN 0-8247-0109-7.
  9. International Journal of Recent Scientific Research. doi:10.24327/IJRSR. ISSN 0976-3031. Missing or empty |title= (help)
  10. . PMID 26389199. Missing or empty |title= (help)
  11. Uzcudun AE, Bravo Fernández P, Sánchez JJ, García Grande A, Rabanal Retolaza I, González Barón M, Gavilán Bouzas J (February 2001). "Clinical features of pharyngeal cancer: a retrospective study of 258 consecutive patients". J Laryngol Otol. 115 (2): 112–8. PMID 11320826.