Cretinism medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
The mainstay of treatment for cretinism is thyroid hormone replacement therapy. levothyroxine (L-T4) is administrated orally to patients with cretinism.
Medical Therapy
- Patients with cretinism are treated with thyroid hormone replacement therapy.
- Endocrine society recommended with the appropriate quick initiation of levothyroxine as the mainstay treatment of cretinism.[1]
- Levothyroxine:
- Life long synthetic levothyroxine (L-T4) is used to treat the cretinism.
- Preferred regimen: 10–15 μg/kg per day orally.
References
- ↑ Léger J, Olivieri A, Donaldson M, Torresani T, Krude H, van Vliet G; et al. (2014). "European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism". J Clin Endocrinol Metab. 99 (2): 363–84. doi:10.1210/jc.2013-1891. PMC 4207909. PMID 24446653.
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