Cretinism classification

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]

Overview

Cretinism may be classified into two groups which include transient and permanent cretinism. Permanent cretinism may classified into two subgroups including primary and secondary cretinism.

Classification

  • Cretinism may be classified based on the duration of thyroid hormones deficiency into two groups:[1]
    • Transient cretinism: Transient deficiency of the thyroid hormones which may be discovered at birth. Thyroid hormone levels returns back to normal after a period of time.
    • Permanent cretinism: Permanent deficiency of the thyroid hormones which requires life long hormonal replacement. Permanent cretinism can be classified into two subgroups based on the location of the etiology:
      • Primary permanent cretinism
      • Secondary (central) permanent cretinism

References

  1. Rastogi MV, LaFranchi SH (2010). "Congenital hypothyroidism". Orphanet J Rare Dis. 5: 17. doi:10.1186/1750-1172-5-17. PMC 2903524. PMID 20537182.

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