Asplenia physical examination

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Kalpana Giri, MBBS[2]

Overview

physical findings depend on the associated anomalies. Patients with sickle cell disease, especially children may have enlarged spleen. Physical exam features typically include Cyanosis, Cold extremities, Stiff neck, Breathlessness, Pan-systolic murmur, Pre-cordial bulge, Ejection systolic murmur, Right sided apex beat, Abdominal tenderness.

Physical Examination

Physical examination of patients with asplenia is:

Vital Signs

Skin

Neck

Lungs

Heart

Cardiovascular examination of patients with asplenia is usually normal. In Right-sided isomerism or Heterotaxy syndromes with complex cardiac anomalies, it revealed:[5]

Abdomen

References

  1. Erdem SB, Genel F, Erdur B, Ozbek E, Gulez N, Mese T (2015). "Asplenia in children with congenital heart disease as a cause of poor outcome". Cent Eur J Immunol. 40 (2): 266–9. doi:10.5114/ceji.2015.52841. PMC 4637402. PMID 26557043.
  2. 2.0 2.1 2.2 Thiruppathy K, Privitera A, Jain K, Gupta S (2008). "Congenital asplenia and group B streptococcus sepsis in the adult: case report and review of the literature". FEMS Immunol Med Microbiol. 53 (3): 437–9. doi:10.1111/j.1574-695X.2008.00422.x. PMID 18564289.
  3. 3.0 3.1 3.2 Iijima S (2017). "Sporadic isolated congenital asplenia with fulminant pneumococcal meningitis: a case report and updated literature review". BMC Infect Dis. 17 (1): 777. doi:10.1186/s12879-017-2896-5. PMC 5735542. PMID 29254492.
  4. 4.0 4.1 4.2 Albrecht T, Poss K, Issaranggoon Na Ayuthaya S, Triden L, Schleiss KL, Schleiss MR (2019). "Case report of congenital asplenia presenting with Haemophilus influenzae type a (Hia) sepsis: an emerging pediatric infection in Minnesota". BMC Infect Dis. 19 (1): 947. doi:10.1186/s12879-019-4572-4. PMC 6842177 Check |pmc= value (help). PMID 31703560.
  5. 5.0 5.1 Agarwal H, Mittal SK, Kulkarni CD, Verma AK, Srivastava SK (2011). "Right isomerism with complex cardiac anomalies presenting with dysphagia--a case report". J Radiol Case Rep. 5 (4): 1–9. doi:10.3941/jrcr.v5i4.702. PMC 3303439. PMID 22470785.

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