Acute cholecystitis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. ; Associate Editor(s)-in-Chief: Dildar Hussain, MBBS 
The majority of patients with cholelithiasis are asymptomatic. Acute cholecystitis occurs as a result of prolonged gallstone obstruction in the bile duct, one to four patients develop biliary colic and about 20% of these patients develop acute cholecystitis annually. The hallmark of acute cholecystitis is biliary colic. A positive history of biliary colic, nausea and vomiting is suggestive of acute cholecystitis.
History and Symptoms
The hallmark of acute cholecystitis is biliary colic. A positive history of biliary colic, nausea and vomiting are suggestive of acute cholecystitis. The most common symptoms of acute cholecystitis are right upper quadrant abdominal or epigastric pain, pain is usually prolonged and there is a positive history of pain after ingestion of heavy fatty meals. The pain is severe and steady and may radiate to the back or right shoulder.
Patients with acute cholecystitis may have a positive history of:
- Advancing age
- Female gender
- Family history
- Genetic factors
- Right upper quadrant abdominal pain
Common symptoms of acute cholecystitis include:
Less Common Symptoms
Less common symptoms of acute cholecystitis include:
- ↑ Friedman GD, Raviola CA, Fireman B (1989). "Prognosis of gallstones with mild or no symptoms: 25 years of follow-up in a health maintenance organization". J Clin Epidemiol. 42 (2): 127–36. PMID 2918322.
- ↑ McSherry CK, Ferstenberg H, Calhoun WF, Lahman E, Virshup M (1985). "The natural history of diagnosed gallstone disease in symptomatic and asymptomatic patients". Ann. Surg. 202 (1): 59–63. PMC 1250837. PMID 4015212.
- ↑ Gracie WA, Ransohoff DF (1982). "The natural history of silent gallstones: the innocent gallstone is not a myth". N. Engl. J. Med. 307 (13): 798–800. doi:10.1056/NEJM198209233071305. PMID 7110244.
- ↑ Carter HR, Cox RL, Polk HC (1987). "Operative therapy for cholecystitis and cholelithiasis: trends over three decades". Am Surg. 53 (10): 565–8. PMID 3426666.
- ↑ Diehl AK (1992). "Symptoms of gallstone disease". Baillieres Clin. Gastroenterol. 6 (4): 635–57. PMID 1486206.
- ↑ Marsicano E, Vuong GM, Prather CM (2014). "Gastrointestinal causes of abdominal pain". Obstet. Gynecol. Clin. North Am. 41 (3): 465–89. doi:10.1016/j.ogc.2014.06.002. PMID 25155126.