Temporal arteritis medical therapy: Difference between revisions
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Prompt treatment with steroids is a medical emergency to reduce the risk of [[blindness]]. | |||
[[Corticosteroid]]s must be started as soon as the diagnosis is suspected (even before the diagnosis is confirmed by biopsy). Steroids do not prevent the diagnosis later being confirmed by biopsy, although certain changes in the histology may be observed towards the end of the first week of treatment and are more difficult to identify after a couple of months.<ref name="pmid16987903">{{cite journal |author=Font RL, Prabhakaran VC |title=Histological parameters helpful in recognising steroid-treated temporal arteritis: an analysis of 35 cases |journal=The British journal of ophthalmology |volume=91 |issue=2 |pages=204–9 |year=2007 |pmid=16987903 |doi=10.1136/bjo.2006.101725}}</ref> | [[Corticosteroid]]s must be started as soon as the diagnosis is suspected (even before the diagnosis is confirmed by biopsy). Steroids do not prevent the diagnosis later being confirmed by biopsy, although certain changes in the histology may be observed towards the end of the first week of treatment and are more difficult to identify after a couple of months.<ref name="pmid16987903">{{cite journal |author=Font RL, Prabhakaran VC |title=Histological parameters helpful in recognising steroid-treated temporal arteritis: an analysis of 35 cases |journal=The British journal of ophthalmology |volume=91 |issue=2 |pages=204–9 |year=2007 |pmid=16987903 |doi=10.1136/bjo.2006.101725}}</ref> |
Revision as of 21:02, 29 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Pharmacotherapy
Acute Pharmacotherapies
Prompt treatment with steroids is a medical emergency to reduce the risk of blindness.
Corticosteroids must be started as soon as the diagnosis is suspected (even before the diagnosis is confirmed by biopsy). Steroids do not prevent the diagnosis later being confirmed by biopsy, although certain changes in the histology may be observed towards the end of the first week of treatment and are more difficult to identify after a couple of months.[1]
A 3 day course of pulse steroids with 250 mg of IV solumedrol BID is critical in reducing the risk of permanent visual loss. If there is progression of visual loss on steroids, IV heparin can be administered to reduce the risk of thrombotic occlusion.
Treatment should not be deferred while waiting on the results of a temporal artery biopsy.
References
- ↑ Font RL, Prabhakaran VC (2007). "Histological parameters helpful in recognising steroid-treated temporal arteritis: an analysis of 35 cases". The British journal of ophthalmology. 91 (2): 204–9. doi:10.1136/bjo.2006.101725. PMID 16987903.