Riedel's thyroiditis medical therapy: Difference between revisions

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*Pharmacologic medical therapies for Riedel's thyroiditis include Corticosteroids and tamoxifen.
*Pharmacologic medical therapies for Riedel's thyroiditis include Corticosteroids and tamoxifen.


===Disease Name===
===Treatment regimen for Riedel's thyroiditis===
As is a Riedel's thyroiditis rare disease the effectiveness of therapy and dosages have not yet been assessed. As a result, dosage regimens and duration of therapy cannot be
defined. The current recommendations are based on the clinical manifestations, associated conditions, and the response to treatment.


*'''Adult'''
*'''Adult'''
** Preferred regimen (1): [[drug name]] 100 mg PO q12h for 10-21 days '''(Contraindications/specific instructions)''' 
** Preferred regimen (1): [[Prednisone]] 15-60mg PO q24h for 6 months to 2 years   
** Preferred regimen (2): [[drug name]] 500 mg PO q8h for 14-21 days
** Preferred regimen (2): [[Prednisone]] 500 mg PO q24h for 6 months to 2 years
***** Alternative regimen (1): [[drug name]] 500 mg PO q6h for 7–10 days
** Alternative regimen (1): [[Tamoxifen]] 10-20 mg PO q24h for 6 months to 2 years
 
** Alternative regimen (1): [[Mycophenolate mofetil]] 1 g PO q12h for 6 months to 2 years
*'''Pediatric'''
*'''Pediatric'''
** Preferred regimen (1): [[drug name]] 50 mg/kg PO per day q8h (maximum, 500 mg per dose) 
** Preferred regimen (1): [[Prednisone]] 15-60mg PO q24h for 6 months to 2 years   
** Preferred regimen (2): [[drug name]] 30 mg/kg PO per day in 2 divided doses (maximum, 500 mg per dose)
** Preferred regimen (2): [[Prednisone]] 500 mg PO q24h for 6 months to 2 years





Revision as of 13:29, 21 August 2017

Riedel's thyroiditis Microchapters

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

The mainstay of treatment for Riedel's thyroiditis is corticosteroid therapy. Tamoxifen has also been proposed as a part of the treatment plan.[1]

Medical Therapy

  • Pharmacologic medical therapies for Riedel's thyroiditis include Corticosteroids and tamoxifen.

Treatment regimen for Riedel's thyroiditis

As is a Riedel's thyroiditis rare disease the effectiveness of therapy and dosages have not yet been assessed. As a result, dosage regimens and duration of therapy cannot be defined. The current recommendations are based on the clinical manifestations, associated conditions, and the response to treatment.

  • Adult
    • Preferred regimen (1): Prednisone 15-60mg PO q24h for 6 months to 2 years
    • Preferred regimen (2): Prednisone 500 mg PO q24h for 6 months to 2 years
    • Alternative regimen (1): Tamoxifen 10-20 mg PO q24h for 6 months to 2 years
    • Alternative regimen (1): Mycophenolate mofetil 1 g PO q12h for 6 months to 2 years
  • Pediatric
    • Preferred regimen (1): Prednisone 15-60mg PO q24h for 6 months to 2 years
    • Preferred regimen (2): Prednisone 500 mg PO q24h for 6 months to 2 years


References

  1. Dabelic N, Jukic T, Labar Z, Novosel SA, Matesa N, Kusic Z (2003). "Riedel's thyroiditis treated with tamoxifen" (PDF). Croat. Med. J. 44 (2): 239–41. PMID 12698518. Unknown parameter |month= ignored (help)

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