Major or mild neurocognitive disorder due to Alzheimer's disease: Difference between revisions
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::*b.Steadily progressive, gradual decline in cognition, without extended plateaus. | ::*b.Steadily progressive, gradual decline in cognition, without extended plateaus. | ||
::*c.No evidence of mixed etiology (i.e., absence of other neurodegenerative or cerebrovascular disease, or another neurological, mental, or systemic disease or condition likely contributing to cognitive decline). | ::*c.No evidence of mixed etiology (i.e., absence of other neurodegenerative or [[cerebrovascular disease]], or another neurological, mental, or systemic disease or condition likely contributing to cognitive decline). | ||
====For mild neurocognitive disorder:==== | ====For mild neurocognitive disorder:==== | ||
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'''''AND''''' | '''''AND''''' | ||
*D.The disturbance is not better explained by [[cerebrovascular disease]], another | *D.The disturbance is not better explained by [[cerebrovascular disease]], another neurodegenerative disease, the effects of a substance, or another mental, neurological, or systemic disorder. | ||
}} | }} | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== |
Revision as of 19:04, 4 November 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]
Overview
Major or Mild Neurocognitive Disorder Due to Alzheimer's Disease
DSM-V Diagnostic Criteria for Major or Mild Neurocognitive Disorder Due to Alzheimer’s Disease [1]
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For major neurocognitive disorder:Probable Alzheimer’s disease is diagnosed if either of the following is present; otherwise, possible Alzheimer’s disease should be diagnosed.
For mild neurocognitive disorder:Probable Alzheimer’s disease is diagnosed if there is evidence of a causative Alzheimer’s disease genetic mutation from either genetic testing or family history. Possible Alzheimer’s disease is diagnosed if there is no evidence of a causative Alzheimer’s disease genetic mutation from either genetic testing or family history, and all three of the following are present:
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Epidemiology and Demographics
Prevalence
The prevalence of major or mild neurocognitive Disorder Due To Alzheimer's Disease is:
7,000 per 100,000 (7%) in ages 65-74 years.
53,000 per 100,000 (53%) in ages 75-84 years.
40,000 per 100,000 (40%) in ages 85 years and older.[1]
Risk Factors
- Age
- Down's syndrome
- Genetic predisposition
- Multiple vascular risk factors
- Traumatic brain injury[1]
Differential Diagnosis
- Major depressive disorder
- Other neurocognitive disorders
- Other concurrent, active neurological or systemic illness