Lysosomal lipase: Difference between revisions
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'''Lysosomal lipase''' is a form of [[lipase]] associated with [[Wolman disease]]. | '''Lysosomal lipase''' is a form of [[lipase]] which functions [[intracellular]]ly, in the [[lysosome]]s. | ||
==Clinical significance== | |||
A deficiency is associated with [[Wolman disease]]. | |||
[[Chlorpromazine]] is an inhibitor of lysosomal lipase.<ref name="pmid4004781">{{cite journal |author=Sauro VS, Klamut HJ, Lin CH, Strickland KP |title=Lysosomal triacylglycerol lipase activity in L6 myoblasts and its changes on differentiation |journal=Biochem. J. |volume=227 |issue=2 |pages=583–9 |year=1985 |pmid=4004781 |doi=}}</ref> | |||
==References== | |||
<references/> | |||
==External links== | ==External links== | ||
Revision as of 20:58, 19 December 2011
| lipase A, lysosomal acid, cholesterol esterase (Wolman disease) | |
|---|---|
| Identifiers | |
| Symbol | LIPA |
| Entrez | 3988 |
| HUGO | 6617 |
| OMIM | 278000 |
| RefSeq | NM_000235 |
| UniProt | P38571 |
| Other data | |
| EC number | 3.1.1.3 |
| Locus | Chr. 10 q23.2-23.3 |
Lysosomal lipase is a form of lipase which functions intracellularly, in the lysosomes.
Clinical significance
A deficiency is associated with Wolman disease.
Chlorpromazine is an inhibitor of lysosomal lipase.[1]
References
External links
- lysosomal+acid+lipase,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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