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{{Lymphomatoid granulomatosis}}
{{Lymphomatoid granulomatosis}}


{{CMG}}; {{AE}}  
{{CMG}}; {{AE}} {{kakbar}}
==Overview==
==Overview==
The risk factor this disease is commonly EBV infection . One my also develop it in a immunodeficient state, organ transplantation , and HIV infection.
The risk factor this disease is commonly [[Epstein Barr virus|EBV]] infection . One my also develop it in a [[Immunodeficiency|immunodeficient]] state, organ transplantation , and [[Human Immunodeficiency Virus (HIV)|HIV]] infection.


==Risk Factors==
==Risk Factors==
The most potent risk factor in the development of Lymphomatoid granulomatosis is EBV infection. Other risk factors include Drug induced immunodeficiency, Immunodeficient diseases, and HIV infection, and organ transplantation.
*The most potent risk factor in the development of [[Lymphomatoid granulomatosis]] is EBV infection. Other risk factors include Drug induced immunodeficiency, Immunodeficient diseases, and HIV infection, and organ transplantation.<ref name="pmid25003566">{{cite journal| author=Neparidze N, Lacy J| title=Malignancies associated with epstein-barr virus: pathobiology, clinical features, and evolving treatments. | journal=Clin Adv Hematol Oncol | year= 2014 | volume= 12 | issue= 6 | pages= 358-71 | pmid=25003566 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25003566  }} </ref><ref name="pmid29518976">{{cite journal| author=Dojcinov SD, Fend F, Quintanilla-Martinez L| title=EBV-Positive Lymphoproliferations of B- T- and NK-Cell Derivation in Non-Immunocompromised Hosts. | journal=Pathogens | year= 2018 | volume= 7 | issue= 1 | pages=  | pmid=29518976 | doi=10.3390/pathogens7010028 | pmc=5874754 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=29518976  }} </ref>


===Common Risk Factors===
===Common Risk Factors===
*Common risk factors in the development of Lymphamatoid granulomatosis include:
*Common risk factors in the development of Lymphamatoid granulomatosis include:
**EBV infection<ref name="pmid25321327">{{cite journal |vauthors=Song JY, Pittaluga S, Dunleavy K, Grant N, White T, Jiang L, Davies-Hill T, Raffeld M, Wilson WH, Jaffe ES |title=Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations |journal=Am. J. Surg. Pathol. |volume=39 |issue=2 |pages=141–56 |date=February 2015 |pmid=25321327 |pmc=4293220 |doi=10.1097/PAS.0000000000000328 |url=}}</ref>
**[[Epstein Barr virus|EBV]] infection<ref name="pmid25321327">{{cite journal |vauthors=Song JY, Pittaluga S, Dunleavy K, Grant N, White T, Jiang L, Davies-Hill T, Raffeld M, Wilson WH, Jaffe ES |title=Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations |journal=Am. J. Surg. Pathol. |volume=39 |issue=2 |pages=141–56 |date=February 2015 |pmid=25321327 |pmc=4293220 |doi=10.1097/PAS.0000000000000328 |url=}}</ref>
**HIV infection<ref name="CostiniukKaramchandani2018">{{cite journal|last1=Costiniuk|first1=Cecilia T.|last2=Karamchandani|first2=Jason|last3=Bessissow|first3=Ali|last4=Routy|first4=Jean-Pierre|last5=Szabo|first5=Jason|last6=Frenette|first6=Charles|title=Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report|journal=BMC Infectious Diseases|volume=18|issue=1|year=2018|issn=1471-2334|doi=10.1186/s12879-018-3128-3}}</ref>
**[[Human Immunodeficiency Virus (HIV)|HIV]] infection<ref name="CostiniukKaramchandani2018">{{cite journal|last1=Costiniuk|first1=Cecilia T.|last2=Karamchandani|first2=Jason|last3=Bessissow|first3=Ali|last4=Routy|first4=Jean-Pierre|last5=Szabo|first5=Jason|last6=Frenette|first6=Charles|title=Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report|journal=BMC Infectious Diseases|volume=18|issue=1|year=2018|issn=1471-2334|doi=10.1186/s12879-018-3128-3}}</ref>
**Drug induced immunodeficiency
**Drug induced immunodeficiency<ref name="BarakatGrover2014">{{cite journal|last1=Barakat|first1=Athar|last2=Grover|first2=Karan|last3=Peshin|first3=Rohit|title=Rituximab for pulmonary lymphomatoid granulomatosis which developed as a complication of methotrexate and azathioprine therapy for rheumatoid arthritis|journal=SpringerPlus|volume=3|issue=1|year=2014|pages=751|issn=2193-1801|doi=10.1186/2193-1801-3-751}}</ref>
**Organ transplantation
**[[Organ transplant|Organ transplantation]]<ref name="ShahSmith2018">{{cite journal|last1=Shah|first1=Sujal|last2=Smith|first2=Megan|last3=Butler|first3=Randall|title=A Case of Hodgkin Lymphoma Mimicking Lymphomatoid Granulomatosis Diagnosed at Autopsy|journal=Laboratory Medicine|volume=49|issue=1|year=2018|pages=80–86|issn=0007-5027|doi=10.1093/labmed/lmx065}}</ref>
 





Latest revision as of 17:30, 19 December 2018

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kamal Akbar, M.D.[2]

Overview

The risk factor this disease is commonly EBV infection . One my also develop it in a immunodeficient state, organ transplantation , and HIV infection.

Risk Factors

  • The most potent risk factor in the development of Lymphomatoid granulomatosis is EBV infection. Other risk factors include Drug induced immunodeficiency, Immunodeficient diseases, and HIV infection, and organ transplantation.[1][2]

Common Risk Factors


References

  1. Neparidze N, Lacy J (2014). "Malignancies associated with epstein-barr virus: pathobiology, clinical features, and evolving treatments". Clin Adv Hematol Oncol. 12 (6): 358–71. PMID 25003566.
  2. Dojcinov SD, Fend F, Quintanilla-Martinez L (2018). "EBV-Positive Lymphoproliferations of B- T- and NK-Cell Derivation in Non-Immunocompromised Hosts". Pathogens. 7 (1). doi:10.3390/pathogens7010028. PMC 5874754. PMID 29518976.
  3. Song JY, Pittaluga S, Dunleavy K, Grant N, White T, Jiang L, Davies-Hill T, Raffeld M, Wilson WH, Jaffe ES (February 2015). "Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations". Am. J. Surg. Pathol. 39 (2): 141–56. doi:10.1097/PAS.0000000000000328. PMC 4293220. PMID 25321327.
  4. Costiniuk, Cecilia T.; Karamchandani, Jason; Bessissow, Ali; Routy, Jean-Pierre; Szabo, Jason; Frenette, Charles (2018). "Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report". BMC Infectious Diseases. 18 (1). doi:10.1186/s12879-018-3128-3. ISSN 1471-2334.
  5. Barakat, Athar; Grover, Karan; Peshin, Rohit (2014). "Rituximab for pulmonary lymphomatoid granulomatosis which developed as a complication of methotrexate and azathioprine therapy for rheumatoid arthritis". SpringerPlus. 3 (1): 751. doi:10.1186/2193-1801-3-751. ISSN 2193-1801.
  6. Shah, Sujal; Smith, Megan; Butler, Randall (2018). "A Case of Hodgkin Lymphoma Mimicking Lymphomatoid Granulomatosis Diagnosed at Autopsy". Laboratory Medicine. 49 (1): 80–86. doi:10.1093/labmed/lmx065. ISSN 0007-5027.

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