Lymphomatoid granulomatosis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kamal Akbar, M.D.[2]

Overview

The risk factor this disease is commonly EBV infection . One my also develop it in a immunodeficient state, organ transplantation , and HIV infection.

Risk Factors

  • The most potent risk factor in the development of Lymphomatoid granulomatosis is EBV infection. Other risk factors include Drug induced immunodeficiency, Immunodeficient diseases, and HIV infection, and organ transplantation.[1][2]

Common Risk Factors


References

  1. Neparidze N, Lacy J (2014). "Malignancies associated with epstein-barr virus: pathobiology, clinical features, and evolving treatments". Clin Adv Hematol Oncol. 12 (6): 358–71. PMID 25003566.
  2. Dojcinov SD, Fend F, Quintanilla-Martinez L (2018). "EBV-Positive Lymphoproliferations of B- T- and NK-Cell Derivation in Non-Immunocompromised Hosts". Pathogens. 7 (1). doi:10.3390/pathogens7010028. PMC 5874754. PMID 29518976.
  3. Song JY, Pittaluga S, Dunleavy K, Grant N, White T, Jiang L, Davies-Hill T, Raffeld M, Wilson WH, Jaffe ES (February 2015). "Lymphomatoid granulomatosis--a single institute experience: pathologic findings and clinical correlations". Am. J. Surg. Pathol. 39 (2): 141–56. doi:10.1097/PAS.0000000000000328. PMC 4293220. PMID 25321327.
  4. Costiniuk, Cecilia T.; Karamchandani, Jason; Bessissow, Ali; Routy, Jean-Pierre; Szabo, Jason; Frenette, Charles (2018). "Angiocentric lymph proliferative disorder (lymphomatoid granulomatosis) in a person with newly-diagnosed HIV infection: a case report". BMC Infectious Diseases. 18 (1). doi:10.1186/s12879-018-3128-3. ISSN 1471-2334.
  5. Barakat, Athar; Grover, Karan; Peshin, Rohit (2014). "Rituximab for pulmonary lymphomatoid granulomatosis which developed as a complication of methotrexate and azathioprine therapy for rheumatoid arthritis". SpringerPlus. 3 (1): 751. doi:10.1186/2193-1801-3-751. ISSN 2193-1801.
  6. Shah, Sujal; Smith, Megan; Butler, Randall (2018). "A Case of Hodgkin Lymphoma Mimicking Lymphomatoid Granulomatosis Diagnosed at Autopsy". Laboratory Medicine. 49 (1): 80–86. doi:10.1093/labmed/lmx065. ISSN 0007-5027.

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