Interstitial nephritis overview
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Interstitial nephritis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohsen Basiri M.D.
Overview
Two main diseases involve the renal tubules are: Acute tubular necrosis due to Ischemic or toxic injury .(for more about ATN click here), and tubulointerstitial nephritis with Inflammatory involvement of tubules and interstitium and its consequent reactions.
Since some cases of TIN are due to bacterial infection, and the renal pelvis is deeply involved, therefore pyelonephritis is term describes this condition; and In general ,the term interstitial nephritis is used for TIN that are owing to nonbacterial causes of tubular injury such as drugs, viral infections,autoimmune systemic diseases , in which these condition mechanism of damage is due to inflammatory responses not direct damage.