FCGR3A
| Fc fragment of IgG, low affinity IIIa, receptor (CD16a) | |||||||||||||
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 PDB rendering based on 1e4j. | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | FCGR3A ; CD16; CD16a; FCG3; FCGR3; IGFR3 | ||||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 477 | ||||||||||||
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| Template:GNF Ortholog box | |||||||||||||
| Species | Human | Mouse | |||||||||||
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| RefSeq (mRNA) | n/a | n/a | |||||||||||
| RefSeq (protein) | n/a | n/a | |||||||||||
| Location (UCSC) | n/a | n/a | |||||||||||
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Fc fragment of IgG, low affinity IIIa, receptor (CD16a), also known as FCGR3A, is a human gene.[1]
References
Further reading
- Anderson P, Caligiuri M, O'Brien C; et al. (1990). "Fc gamma receptor type III (CD16) is included in the zeta NK receptor complex expressed by human natural killer cells". Proc. Natl. Acad. Sci. U.S.A. 87 (6): 2274–8. PMID 2138330.
- Qiu WQ, de Bruin D, Brownstein BH; et al. (1990). "Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination". Science. 248 (4956): 732–5. PMID 2139735.
- Le Coniat M, Kinet JP, Berger R (1990). "The human genes for the alpha and gamma subunits of the mast cell receptor for immunoglobulin E are located on human chromosome band 1q23". Immunogenetics. 32 (3): 183–6. PMID 2146219.
- Ory PA, Clark MR, Kwoh EE; et al. (1989). "Sequences of complementary DNAs that encode the NA1 and NA2 forms of Fc receptor III on human neutrophils". J. Clin. Invest. 84 (5): 1688–91. PMID 2478590.
- Peltz GA, Grundy HO, Lebo RV; et al. (1989). "Human Fc gamma RIII: cloning, expression, and identification of the chromosomal locus of two Fc receptors for IgG". Proc. Natl. Acad. Sci. U.S.A. 86 (3): 1013–7. PMID 2521732.
- Scallon BJ, Scigliano E, Freedman VH; et al. (1989). "A human immunoglobulin G receptor exists in both polypeptide-anchored and phosphatidylinositol-glycan-anchored forms". Proc. Natl. Acad. Sci. U.S.A. 86 (13): 5079–83. PMID 2525780.
- Ravetch JV, Perussia B (1989). "Alternative membrane forms of Fc gamma RIII(CD16) on human natural killer cells and neutrophils. Cell type-specific expression of two genes that differ in single nucleotide substitutions". J. Exp. Med. 170 (2): 481–97. PMID 2526846.
- Simmons D, Seed B (1988). "The Fc gamma receptor of natural killer cells is a phospholipid-linked membrane protein". Nature. 333 (6173): 568–70. doi:10.1038/333568a0. PMID 2967436.
- Indik ZK, Hunter S, Huang MM; et al. (1994). "The high affinity Fc gamma receptor (CD64) induces phagocytosis in the absence of its cytoplasmic domain: the gamma subunit of Fc gamma RIIIA imparts phagocytic function to Fc gamma RI". Exp. Hematol. 22 (7): 599–606. PMID 7516890.
- Detmers PA, Zhou D, Powell D; et al. (1995). "Endotoxin receptors (CD14) are found with CD16 (Fc gamma RIII) in an intracellular compartment of neutrophils that contains alkaline phosphatase". J. Immunol. 155 (4): 2085–95. PMID 7543538.
- Morcos M, Hänsch GM, Schönermark M; et al. (1995). "Human glomerular mesangial cells express CD16 and may be stimulated via this receptor". Kidney Int. 46 (6): 1627–34. PMID 7700021.
- Schumann G, Dasgupta JD (1995). "Specificity of signal transduction through CD16, TCR-CD3 and BCR receptor chains containing the tyrosine-associated activation motif". Int. Immunol. 6 (9): 1383–92. PMID 7819147.
- Gessner JE, Grussenmeyer T, Kolanus W, Schmidt RE (1995). "The human low affinity immunoglobulin G Fc receptor III-A and III-B genes. Molecular characterization of the promoter regions". J. Biol. Chem. 270 (3): 1350–61. PMID 7836402.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. PMID 8125298.
- Altin JG, Pagler EB, Kinnear BF, Warren HS (1994). "Molecular associations involving CD16, CD45 and zeta and gamma chains on human natural killer cells". Immunol. Cell Biol. 72 (1): 87–96. PMID 8157290.
- Pignata C, Prasad KV, Robertson MJ; et al. (1994). "Fc gamma RIIIA-mediated signaling involves src-family lck in human natural killer cells". J. Immunol. 151 (12): 6794–800. PMID 8258691.
- Cone JC, Lu Y, Trevillyan JM; et al. (1993). "Association of the p56lck protein tyrosine kinase with the Fc gamma RIIIA/CD16 complex in human natural killer cells". Eur. J. Immunol. 23 (10): 2488–97. PMID 8405050.
- de Haas M, Koene HR, Kleijer M; et al. (1996). "A triallelic Fc gamma receptor type IIIA polymorphism influences the binding of human IgG by NK cell Fc gamma RIIIa". J. Immunol. 156 (8): 3948–55. PMID 8609432.
- Gessner JE, Grussenmeyer T, Dumbsky M, Schmidt RE (1997). "Separate promoters from proximal and medial control regions contribute to the natural killer cell-specific transcription of the human FcgammaRIII-A (CD16-A) receptor gene". J. Biol. Chem. 271 (48): 30755–64. PMID 8940055.
- Koene HR, Kleijer M, Algra J; et al. (1997). "Fc gammaRIIIa-158V/F polymorphism influences the binding of IgG by natural killer cell Fc gammaRIIIa, independently of the Fc gammaRIIIa-48L/R/H phenotype". Blood. 90 (3): 1109–14. PMID 9242542.
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