Differentiating Diabetes mellitus type 2 from other diseases: Difference between revisions

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{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
! rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;"|Disease
! rowspan="2" align="center" style="background:#DCDCDC;"|Disease
! colspan="5" align="center" style="background:#4479BA; color: #FFFFFF;"|History and symptoms
! colspan="5" align="center" style="background:#DCDCDC;"|History and symptoms
! colspan="8" align="center" style="background:#4479BA; color: #FFFFFF;"|Laboratory findings
! colspan="8" align="center" style="background:#DCDCDC;"|Laboratory findings
! rowspan="2" align="center" style="background:#4479BA; color: #FFFFFF;"|Additional findings
! rowspan="2" align="center" style="background:#DCDCDC;"|Additional findings
|-
|-
!align="center" style="background:#4479BA; color: #FFFFFF;"|Polyuria
!align="center" style="background:#DCDCDC;"|[[Polyuria]]
!align="center" style="background:#4479BA; color: #FFFFFF;"|Polydipsia
!align="center" style="background:#DCDCDC;"|[[Polydipsia]]
!align="center" style="background:#4479BA; color: #FFFFFF;"|Polyphagia
!align="center" style="background:#DCDCDC;"|[[Polyphagia]]
!align="center" style="background:#4479BA; color: #FFFFFF;"|Weight loss
!align="center" style="background:#DCDCDC;"|[[Weight loss]]
!align="center" style="background:#4479BA; color: #FFFFFF;"|Weight gain
!align="center" style="background:#DCDCDC;"|[[Weight gain]]
!align="center" style="background:#4479BA; color: #FFFFFF;"|Serum glucose
!align="center" style="background:#DCDCDC;"|[[Serum glucose]]
!align="center" style="background:#4479BA; color: #FFFFFF;"|Urinary Glucose
!align="center" style="background:#DCDCDC;"|Urinary Glucose
!align="center" style="background:#4479BA; color: #FFFFFF;"|Urine PH
!align="center" style="background:#DCDCDC;"|Urine PH
!align="center" style="background:#4479BA; color: #FFFFFF;"|Serum Sodium
!align="center" style="background:#DCDCDC;"|[[Sodium|Serum Sodium]]
!align="center" style="background:#4479BA; color: #FFFFFF;"|Urinary Glucose
!align="center" style="background:#DCDCDC;"|Urinary Glucose
!align="center" style="background:#4479BA; color: #FFFFFF;"|24 hrs cortisol level
!align="center" style="background:#DCDCDC;"|24 hrs [[cortisol]] level
!align="center" style="background:#4479BA; color: #FFFFFF;"|C-peptide level
!align="center" style="background:#DCDCDC;"|[[C-peptide]] level
!align="center" style="background:#4479BA; color: #FFFFFF;"|Serum glucagon
!align="center" style="background:#DCDCDC;"|Serum [[glucagon]]
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diabetes mellitus type 1|Type 1 Diabetes mellitus]]
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[Diabetes mellitus type 1|Type 1 Diabetes mellitus]]
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|style="padding: 5px 5px; background: #F5F5F5;" align="center" |N/'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |N/'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |N/'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |N/'''↑'''
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Acanthosis nigricans|Acanthosis nigricans,]]  
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Acanthosis nigricans|Acanthosis nigricans]]  
|-
|-
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[RTA|RTA 1]]
|style="padding: 5px 5px; background: #DCDCDC;" align="center" |[[RTA|RTA 1]]
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|style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Moon face]], [[obesity]], [[buffalo hump]], easy [[Bruising|bruisibility]]
|style="padding: 5px 5px; background: #F5F5F5;" align="center" |[[Moon face]], [[obesity]], [[buffalo hump]], easy [[Bruising|bruisibility]]
|}
|}


==References==
==References==

Revision as of 21:12, 8 March 2017

Diabetes mellitus main page

Diabetes mellitus type 2 Microchapters

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Differentiating Diabetes Mellitus Type 2 from other Diseases

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Differentiating Diabetes Mellitus Type 2 from other Diseases

Differential diagnosis of type 2 DM, include: [1][2][3]

Disease History and symptoms Laboratory findings Additional findings
Polyuria Polydipsia Polyphagia Weight loss Weight gain Serum glucose Urinary Glucose Urine PH Serum Sodium Urinary Glucose 24 hrs cortisol level C-peptide level Serum glucagon
Type 1 Diabetes mellitus ✔ ✔ ✔ ✔ - ↑ ↑ Normal Normal N/↑ Normal ↓ Normal Auto antibodies present (Anti GAD-65 and anti insulin anti bodies)
Type 2 Diabetes mellitus ✔ ✔ ✔ ✔ - ↑ ↑ Normal Normal ↑ Normal Normal ↑ Acanthosis nigricans
MODY ✔ ✔ ✔ - ✔ ↑ ↑ Normal Normal ↑ Normal Normal N -
Psychogenic polydipsia ✔ ✔ - - - Normal Normal Normal ↓ Normal Normal Normal Normal -
Diabetes insipidus ✔ ✔ - - - Normal Normal Normal ↑ Normal Normal Normal Normal -
Transient hyperglycemia - - - - - ↑ ↑ Normal Normal ↑ Normal Normal N/↑ In hospitalized patients especially in ICU and CCU
Steroid therapy ✔ - - - ✔ ↑ ↑ Normal Normal ↑ ↑ N/↑ N/↑ Acanthosis nigricans
RTA 1 - - - ✔ - Normal Normal ↑ Normal ↑ Normal Normal Normal Hypokalemia, nephrolithiasis
Glucagonoma - - - - - ↑ Normal Normal Normal - Normal Normal ↑ Necrolytic migratory erythema
Cushing syndrome - - - - ✔ ↑ - Normal ↓ N/↑ ↑ Normal Normal Moon face, obesity, buffalo hump, easy bruisibility


References

  1. ↑ Barrett TG (2007). "Differential diagnosis of type 1 diabetes: which genetic syndromes need to be considered?". Pediatr Diabetes. 8 Suppl 6: 15–23. doi:10.1111/j.1399-5448.2007.00278.x. PMID 17727381.
  2. ↑ Type 1 Diabetes mellitus "Dennis Kasper, Anthony Fauci, Stephen Hauser, Dan Longo, J. Larry Jameson, Joseph Loscalzo"Harrison's Principles of Internal Medicine, 19e Accessed on December 27th,2016
  3. ↑ "namrata".

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