Diabetes mellitus type 1 historical perspective: Difference between revisions
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==Overview== | ==Overview== | ||
Term "diabetes" was first described in the literature by a Egyptian scientist Eberes papyrus in 1500 BC. Discovery of insulin by Friedrick Banting in 1921-22, was considered as an important landmark in understanding the nature of disease. | Term "diabetes" was first described in the literature by a Egyptian scientist Eberes papyrus in 1500 BC. Discovery of insulin by Friedrick Banting in 1921-22, was considered as an important landmark in understanding the nature of disease. In 1970, the autoimmune nature of the [[type 1 diabetes]] has been discovered. | ||
==Historical Perspective== | ==Historical Perspective== | ||
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** In 1930's, Harold Himsworth demonstrated the effect of [[insulin]] [[Injection (medicine)|injection]] in patients who swallowed a simultaneous dose of [[glucose]]. | ** In 1930's, Harold Himsworth demonstrated the effect of [[insulin]] [[Injection (medicine)|injection]] in patients who swallowed a simultaneous dose of [[glucose]]. | ||
** In 1951, John Lister concluded that there were two broad groups of diabetics: The young, thin, non-arteriosclerotic group with normal [[blood pressure]] and usually an acute onset to the disease and the older, [[obesity|obese]], [[Atherosclerosis|arteriosclerotic]] group with [[hypertension]] and usually an insidious onset. | ** In 1951, John Lister concluded that there were two broad groups of diabetics: The young, thin, non-arteriosclerotic group with normal [[blood pressure]] and usually an acute onset to the disease and the older, [[obesity|obese]], [[Atherosclerosis|arteriosclerotic]] group with [[hypertension]] and usually an insidious onset. | ||
** In 1970's, [[Diabetes mellitus type 1|type 1 diabetes]] was described as an [[autoimmune disease]] in the 1970s, based on observations that [[autoantibody|autoantibodies]] against [[Islets of Langerhans|islets]] were discovered in diabetics with other | ** In 1970's, [[Diabetes mellitus type 1|type 1 diabetes]] was described as an [[autoimmune disease]] in the 1970s, based on observations that [[autoantibody|autoantibodies]] against [[Islets of Langerhans|islets]] were discovered in diabetics with other [[autoimmune disease|autoimmune deficiencies]]. | ||
** In 1980's, [[Immunosuppressive|Immunosuppressive therapies]] could slow disease progression, further supporting the idea that [[Diabetes mellitus type 1|type 1 diabetes]] is an | ** In 1980's, [[Immunosuppressive|Immunosuppressive therapies]] could slow disease progression, further supporting the idea that [[Diabetes mellitus type 1|type 1 diabetes]] is an [[autoimmune disease|autoimmune disorder]]. | ||
** In 1996, [[World Health Organization|World Health Organization (WHO)]] opted for a classification based upon [[Etiology|aetiology]], and [[Diabetes mellitus type 1|type 1]] and [[Diabetes mellitus type 2|type 2 diabetes]] became the accepted terms. | ** In 1996, [[World Health Organization|World Health Organization (WHO)]] opted for a classification based upon [[Etiology|aetiology]], and [[Diabetes mellitus type 1|type 1]] and [[Diabetes mellitus type 2|type 2 diabetes]] became the accepted terms. | ||
Latest revision as of 19:40, 22 August 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Vishal Devarkonda, M.B.B.S[2]
Overview
Term "diabetes" was first described in the literature by a Egyptian scientist Eberes papyrus in 1500 BC. Discovery of insulin by Friedrick Banting in 1921-22, was considered as an important landmark in understanding the nature of disease. In 1970, the autoimmune nature of the type 1 diabetes has been discovered.
Historical Perspective
- Historically diabetes is an ancient disease, Term diabetes was first described in the literature by Egyptian scientist Eberes papyrus, around 1500 BC.[1]
- The following are important events in understanding of diabetes history:[2][3][4][5][6]
- In 1866, Harley reported two distinct forms of disease requiring diametrically opposing form of treatment.
- In 1921-22, Canadian physician Fredrick Banting and medical student Charles H. Best were credited with discovering the hormone insulin in the pancreatic extracts of dogs.
- In 1930's, Harold Himsworth demonstrated the effect of insulin injection in patients who swallowed a simultaneous dose of glucose.
- In 1951, John Lister concluded that there were two broad groups of diabetics: The young, thin, non-arteriosclerotic group with normal blood pressure and usually an acute onset to the disease and the older, obese, arteriosclerotic group with hypertension and usually an insidious onset.
- In 1970's, type 1 diabetes was described as an autoimmune disease in the 1970s, based on observations that autoantibodies against islets were discovered in diabetics with other autoimmune deficiencies.
- In 1980's, Immunosuppressive therapies could slow disease progression, further supporting the idea that type 1 diabetes is an autoimmune disorder.
- In 1996, World Health Organization (WHO) opted for a classification based upon aetiology, and type 1 and type 2 diabetes became the accepted terms.
References
- ↑ "Diabetes. medicine".
- ↑ "Diabetes in control".
- ↑ Banting FG, Best CH, Collip JB, Campbell WR, Fletcher AA (1991). "Pancreatic extracts in the treatment of diabetes mellitus: preliminary report. 1922". CMAJ. 145 (10): 1281–6. PMC 1335942. PMID 1933711.
- ↑ "diabetes.org".
- ↑ "history of type 1 diabetes".
- ↑ "diabetes health".