Deoxyribonuclease II
| deoxyribonuclease II alpha | |
|---|---|
| Identifiers | |
| Symbol | DNASE2 |
| Alt. symbols | DNASE2A, DRN2, DNL, DNL2 |
| Entrez | 1777 |
| HUGO | 2960 |
| OMIM | 126350 |
| RefSeq | NM_001375 |
| UniProt | O00115 |
| Other data | |
| EC number | 3.1.22.1 |
| Locus | Chr. 19 p13.2 |
| deoxyribonuclease II beta | |
|---|---|
| Identifiers | |
| Symbol | DNASE2B |
| Entrez | 58511 |
| HUGO | 28875 |
| OMIM | 608057 |
| RefSeq | NM_021233 |
| UniProt | Q8WZ79 |
| Other data | |
| EC number | 3.1.22.1 |
| Locus | Chr. 1 p22.3 |
Deoxyribonuclease II (EC 3.1.22.1, DNase II, pancreatic DNase II, deoxyribonucleate 3'-nucleotidohydrolase, pancreatic DNase II, acid deoxyribonuclease, acid DNase) hydrolyzes deoxyribonucleotide linkages in native and denatured DNA, yielding products with 3'-phosphates. As the name implies, it is more effective at acid pH.
There are several known DNases II, including:
- DNase II alpha (usually just called DNase II)
- DNase II beta (also called DLAD, or DNase II-Like Acid DNase)
External links
- deoxyribonuclease+II at the US National Library of Medicine Medical Subject Headings (MeSH)
| This EC 3.1 enzyme-related article is a stub. You can help Wikipedia by expanding it. |